Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2

Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2

Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune system in mediating these clinical outcomes has not been determined. We used multiparameter flow cytometry and systems serology to comprehen...

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Main Authors: Yu, Krystle K.Q (Author), Fischinger, Stephanie (Author), Smith, Malisa T. (Author), Atyeo, Caroline (Author), Cizmeci, Deniz (Author), Wolf, Caitlin R. (Author), Layton, Erik D. (Author), Logue, Jennifer K. (Author), Aguilar, Melissa S. (Author), Shuey, Kiel (Author), Loos, Carolin (Author), Yu, Jingyou (Author), Franko, Nicholas (Author), Choi, Robert Y. (Author), Wald, Anna (Author), Barouch, Dan (Author), Koelle, David M. (Author), Lauffenburger, Douglas (Author), Chu, Helen Y. (Author), Alter, Galit (Author), Seshadri, Chetan (Author)
Other Authors: Ragon Institute of MGH, MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: American Society for Clinical Investigation, 2021-05-12T20:21:13Z.
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