Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1

Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1

© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc. Approximately 20-30% of human lung adenocarcinomas (LUADs) harbor mutations in Kelch-like ECH-associated protein 1 (KEAP1) that hyperactivate the nuclear factor, erythroid 2-like 2 (NFE2L2) antioxidant program. We previo...

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Main Authors: Romero, Rodrigo (Author), Sánchez-Rivera, Francisco J (Author), Westcott, Peter MK (Author), Mercer, Kim L (Author), Bhutkar, Arjun (Author), Muir, Alexander (Author), González Robles, Tania J (Author), Lamboy Rodríguez, Swanny (Author), Liao, Laura Z (Author), Ng, Sheng Rong (Author), Li, Leanne (Author), Colón, Caterina I (Author), Naranjo, Santiago (Author), Beytagh, Mary Clare (Author), Lewis, Caroline A (Author), Hsu, Peggy P (Author), Bronson, Roderick T (Author), Vander Heiden, Matthew G (Author), Jacks, Tyler (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-10-25T18:57:39Z.
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