Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1
© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc. Approximately 20-30% of human lung adenocarcinomas (LUADs) harbor mutations in Kelch-like ECH-associated protein 1 (KEAP1) that hyperactivate the nuclear factor, erythroid 2-like 2 (NFE2L2) antioxidant program. We previo...
Main Authors: | , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2021-10-25T18:57:39Z.
|
Subjects: | |
Online Access: | Get fulltext |