Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers

© 2016 Elsevier Inc. Generic spinal motor neuron identity is established by cooperative binding of programming transcription factors (TFs), Isl1 and Lhx3, to motor-neuron-specific enhancers. How expression of effector genes is maintained following downregulation of programming TFs in maturing neuron...

Full description

Bibliographic Details
Main Authors: Rhee, Ho Sung (Author), Closser, Michael (Author), Guo, Yuchun (Author), Bashkirova, Elizaveta V (Author), Tan, G Christopher (Author), Gifford, David K (Author), Wichterle, Hynek (Author)
Format: Article
Language:English
Published: Elsevier BV, 2021-10-27T20:29:02Z.
Subjects:
Online Access:Get fulltext