Inferring the intrinsic mutational fitness landscape of influenzalike evolving antigens from temporally ordered sequence data

There still are no effective long-term protective vaccines against viruses that continuously evolve under immune pressure such as seasonal influenza, which has caused, and can cause, devastating epidemics in the human population. To find such a broadly protective immunization strategy, it is useful...

Full description

Bibliographic Details
Main Authors: Doelger, Julia (Author), Kardar, Mehran (Author), Chakraborty, Arup K (Author)
Format: Article
Language:English
Published: American Physical Society (APS), 2022-04-20T17:54:43Z.
Subjects:
Online Access:Get fulltext