The role of the CD[subscript 5]8 locus in multiple sclerosis

The role of the CD[subscript 5]8 locus in multiple sclerosis

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system associated with demyelination and axonal loss. A whole genome association scan suggested that allelic variants in the CD58 gene region, encoding the costimulatory molecule LFA-3, are associated with risk of developing M...

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Main Authors: De Jager, Philip L. (Contributor), Baecher-Allan, Clare (Author), Maier, Lisa M. (Contributor), Arthur, Ariel T. (Author), Ottoboni, Linda (Contributor), Barcellos, Lisa F. (Author), McCauley, Jacob L. (Author), Sawcer, Stephen (Author), Goris, An (Author), Saarela, Janna (Author), Yelensky, Roman (Author), Price, Alkes (Contributor), Leppa, Virpi (Author), Patterson, Nick (Contributor), de Bakker, Paul I. W. (Contributor), Tran, Dong (Contributor), Aubin, Cristin (Contributor), Pobywajlo, Susan (Author), Rossin, Elizabeth (Contributor), Hu, Xinli (Contributor), Ashley, Charles W. (Author), Choy, Edwin (Contributor), Rioux, John D. (Contributor), Pericak-Vance, Margaret A. (Author), Ivinson, Adrian (Author), Booth, David R. (Author), Stewart, Graeme J. (Author), Palotie, Aarno (Contributor), Peltonen, Leena (Contributor), Dubois, Benedicte (Author), Haines, Jonathan L. (Author), Weiner, Howard L. (Author), Compston, Alastair (Author), Hauser, Stephen L. (Author), Daly, Mark J. (Contributor), Reich, David (Contributor), Oksenberg, Jorge R. (Author), Hafler, David A. (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2009-12-28T18:39:52Z.
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