Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns have implicated these lincRNAs in diverse biological processes, including cell-cycle regulation, immune surve...

Full description

Bibliographic Details
Main Authors: Presser, Aviva (Contributor), Guttman, Mitchell (Contributor), Raj, Arjun (Contributor), van Oudenaarden, Alexander (Contributor), Rinn, John L. (Author), Lander, Eric S. (Author), Regev, Aviv (Author), Bernstein, Bradley E. (Author), Thomas, Kelly (Author), Morales, Dianali Rivea (Author), Garber, Manuel (Author), Khalil, Ahmad M. (Author), Huarte, Maite (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor)
Format: Article
Language:English
Published: United States National Academy of Sciences, 2010-03-12T19:32:47Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items