Structural basis for the inhibition of human alkyladenine DNA by 3,N4-ethenocytosine containing DNA

Structural basis for the inhibition of human alkyladenine DNA by 3,N4-ethenocytosine containing DNA

Reactive oxygen and nitrogen species, generated by neutrophils and macrophages in chronically inflamed tissues, readily damage DNA, producing a variety of potentially genotoxic etheno base lesions; such inflammation-related DNA damage is now known to contribute to carcinogenesis. Although the human...

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Main Authors: Lingaraju, Gondichatnahalli M. (Contributor), Davis, Christopher A. (Contributor), Setser, Jeremy Wayne (Contributor), Samson, Leona D (Author), Drennan, Catherine L (Author)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Drennan, Catherine L. (Contributor), Samson, Leona D. (Contributor)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology, Inc., 2011-06-30T18:29:55Z.
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