3-Ketoacyl thiolase delays aging of Caenorhabditis elegans and is required for lifespan extension mediated by sir-2.1

Studies of long-lived Caenorhabditis elegans mutants have identified several genes that function to limit lifespan, i.e., loss-of-function mutations in these genes promote longevity. By contrast, little is known about genes that normally act to delay aging and that when mutated cause premature aging...

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Bibliographic Details
Main Authors: Berdichevsky, Alina (Contributor), Nedelcu, Simona (Contributor), Boulias, Konstantinos (Contributor), Bishop, Nicholas A. (Contributor), Guarente, Leonard Pershing (Contributor), Horvitz, Howard Robert (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Paul F. Glenn Center for Biology of Aging Research (Massachusetts Institute of Technology) (Contributor), Horvitz, H. Robert (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2011-07-14T17:39:30Z.
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