Predicting the binding preference of transcription factors to individual DNA k-mers

Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly characterized, in part due to the difficulty associated with determining their specificity experimentally...

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Bibliographic Details
Main Authors: Bulyk, Martha L. (Contributor), Philippakis, Anthony A. (Contributor), Alleyne, Trevis M. (Author), Peña-Castillo, Lourdes (Author), Badis, Gwenael (Author), Talukder, Shaheynoor (Author), Berger, Michael F. (Author), Gehrke, Andrew R. (Author), Morris, Quaid D. (Author), Hughes, Timothy R. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2012-09-26T14:41:46Z.
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