lincRNAs act in the circuitry controlling pluripotency and differentiation

lincRNAs act in the circuitry controlling pluripotency and differentiation

Although thousands of large intergenic non-coding RNAs (lincRNAs) have been identified in mammals, few have been functionally characterized, leading to debate about their biological role. To address this, we performed loss-of-function studies on most lincRNAs expressed in mouse embryonic stem (ES) c...

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Main Authors: Guttman, Mitchell (Contributor), Donaghey, Julie (Author), Carey, Bryce W. (Contributor), Garber, Manuel (Author), Grenier, Jennifer K. (Author), Munson, Glen (Author), Young, Geneva (Author), Lucas, Anne Bergstom (Author), Ach, Robert (Author), Bruhn, Laurakay (Author), Yang, Xiaoping (Author), Amit, Ido (Author), Meissner, Alexander (Author), Regev, Aviv (Contributor), Rinn, John L. (Author), Root, David E. (Author), Lander, Eric Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2012-10-18T18:49:32Z.
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