Engineered gp120 immunogens that elicit VRC01-like antibodies by vaccination
Background: One of the great challenges for an HIV vaccine is to elicit broadly neutralizing antibodies specific for conserved epitopes from which the virus cannot easily escape. The CD4 binding site is one such epitope against which several antibodies (e.g. b12, VRC01) have been isolated. In macaqu...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Biomed Central Ltd.,
2013-01-30T15:56:26Z.
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| Subjects: | |
| Online Access: | Get fulltext |