Dynamic Modeling of Cell Migration and Spreading Behaviors on Fibronectin Coated Planar Substrates and Micropatterned Geometries

An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration behaviors. This work is motivated by two experimental works: (1) cell migrat...

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Bibliographic Details
Main Authors: Kim, Min-Cheol (Contributor), Kamm, Roger Dale (Contributor), Neal, Devin M (Author), Asada, Haruhiko (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. School of Engineering (Contributor), Singapore-MIT Alliance in Research and Technology (SMART) (Contributor), Neal, Devin M. (Contributor), Asada, Harry (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-04-11T14:45:12Z.
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