Stochastic Cytokine Expression Induces Mixed T Helper Cell States

Stochastic Cytokine Expression Induces Mixed T Helper Cell States

During eukaryotic development, the induction of a lineage-specific transcription factor typically drives differentiation of multipotent progenitor cells, while repressing that of alternative lineages. This process is often mediated by some extracellular signaling molecules, such as cytokines that ca...

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Bibliographic Details
Main Authors: Fang, Miaoqing (Contributor), Xie, Huangming (Author), Dougan, Stephanie K. (Author), Ploegh, Hidde (Contributor), van Oudenaarden, Alexander (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-09-27T14:54:29Z.
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