Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

The major histocompatibility complex (MHC) region is strongly associated with multiple sclerosis (MS) susceptibility. HLA-DRB1*15:01 has the strongest effect, and several other alleles have been reported at different levels of validation. Using SNP data from genome-wide studies, we imputed and teste...

Full description

Bibliographic Details
Main Authors: Patsopoulos, Nikolaos A. (Author), Barcellos, Lisa F. (Author), Hintzen, Rogier Q. (Author), Schaefer, Catherine (Author), van Duijn, Cornelia M. (Author), Noble, Janelle A. (Author), Raj, Towfique (Author), Gourraud, Pierre-Antoine (Author), Stranger, Barbara E. (Author), Oksenberg, Jorge (Author), Olsson, Tomas (Author), Taylor, Bruce V. (Author), Sawcer, Stephen (Author), Hafler, David A. (Contributor), Carrington, Mary (Author), De Jager, Philip L. (Author), de Bakker, Paul I. W. (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-12-30T20:34:50Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items