Initial genome sequencing and analysis of multiple myeloma

Initial genome sequencing and analysis of multiple myeloma

Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38 tumour genomes and their comparison to matched normal DNAs. Several new and unexpected oncogenic mechanisms were suggested by the pattern of...

Full description

Bibliographic Details
Main Authors: Chapman, Michael A. (Author), Lawrence, Michael S. (Author), Keats, Jonathan J. (Author), Cibulskis, Kristian (Author), Sougnez, Carrie (Author), Schinzel, Anna C. (Author), Harview, Christina L. (Author), Brunet, Jean-Philippe (Author), Ahmann, Gregory J. (Author), Adli, Mazhar (Author), Anderson, Kenneth C. (Author), Ardlie, Kristin (Author), Auclair, Daniel (Author), Baker, Angela (Author), Bergsagel, P. Leif (Author), Bernstein, Bradley E. (Author), Drier, Yotam (Author), Fonseca, Rafael (Author), Gabriel, Stacey B. (Author), Lander, Eric Steven (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-01-31T20:11:30Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items