Predicting cancer drug mechanisms of action using molecular network signatures

Predicting cancer drug mechanisms of action using molecular network signatures

Molecular signatures are a powerful approach to characterize novel small molecules and derivatized small molecule libraries. While new experimental techniques are being developed in diverse model systems, informatics approaches lag behind these exciting advances. We propose an analysis pipeline for...

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Bibliographic Details
Main Authors: Pritchard, Justin R. (Contributor), Bruno, Peter Michael (Contributor), Hemann, Michael (Contributor), Lauffenburger, Douglas A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Lauffenburger, Douglas A. (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2014-08-22T15:50:00Z.
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