Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection

Neutralizing (nAbs) and high affinity binding antibodies may be critical for an efficacious HIV-1 vaccine. We characterized virus-specific nAbs and binding antibody responses over 21 months in eight HIV-1 subtype C chronically infected individuals with heterogeneous rates of disease progression. Aut...

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Main Authors: Archary, Derseree (Author), Rong, Rong (Author), Gordon, Michelle L. (Author), Boliar, Saikat (Author), Madiga, Maphuti (Author), Gray, Elin S. (Author), Dugast, Anne-Sophie (Author), Hermanus, Tandile (Author), Goulder, Philip J. R. (Author), Coovadia, Hoosen M. (Author), Werner, Lise (Author), Morris, Lynn (Author), Alter, Galit (Contributor), Derdeyn, Cynthia A. (Author), Ndung'u, Thumbi (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-09-22T18:07:33Z.
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