Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells
Valency requirements for B cell activation upon antigen encounter are poorly understood. OB1 transnuclear B cells express an IgG1 B cell receptor (BCR) specific for ovalbumin (OVA), the epitope of which can be mimicked using short synthetic peptides to allow antigen-specific engagement of the BCR. B...
Main Authors: | , , , , , , , , , , , |
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Other Authors: | , , , , , , |
Format: | Article |
Language: | English |
Published: |
Rockefeller University Press,
2014-09-25T17:10:49Z.
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Subjects: | |
Online Access: | Get fulltext |