Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

Human immunodeficiency virus type 1 (HIV-1)-specific monoclonal antibodies with extraordinary potency and breadth have recently been described. In humanized mice, combinations of monoclonal antibodies have been shown to suppress viraemia, but the therapeutic potential of these monoclonal antibodies...

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Bibliographic Details
Main Authors: Barouch, Dan H. (Contributor), Whitney, James B. (Author), Moldt, Brian (Author), Klein, Florian (Author), Oliveira, Thiago Y. (Author), Liu, Jinyan (Author), Stephenson, Kathryn E. (Author), Chang, Hui-Wen (Author), Shekhar, Karthik (Contributor), Gupta, Sanjana (Contributor), Nkolola, Joseph P. (Author), Seaman, Michael S. (Author), Smith, Kaitlin M. (Author), Borducchi, Erica N. (Author), Cabral, Crystal (Author), Smith, Jeffrey Y. (Author), Blackmore, Stephen (Author), Sanisetty, Srisowmya (Author), Perry, James R. (Author), Beck, Matthew (Author), Lewis, Mark G. (Author), Rinaldi, William (Author), Poignard, Pascal (Author), Nussenzweig, Michel C. (Author), Burton, Dennis R. (Contributor), Chakraborty, Arup K (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Chakraborty, Arup K. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-10-30T15:11:01Z.
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