Effect of Small-Molecule-Binding Affinity on Tumor Uptake In Vivo: A Systematic Study Using a Pretargeted Bispecific Antibody
Small-molecule ligands specific for tumor-associated surface receptors have wide applications in cancer diagnosis and therapy. Achieving high-affinity binding to the desired target is important for improving detection limits and for increasing therapeutic efficacy. However, the affinity required for...
| Main Authors: | , , , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
American Association for Cancer Research,
2014-11-20T14:50:02Z.
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| Subjects: | |
| Online Access: | Get fulltext |