Generation of Effector Memory T Cell-Based Mucosal and Systemic Immunity with Pulmonary Nanoparticle Vaccination

Generation of Effector Memory T Cell-Based Mucosal and Systemic Immunity with Pulmonary Nanoparticle Vaccination

Many pathogens infiltrate the body and initiate infection via mucosal surfaces. Hence, eliciting cellular immune responses at mucosal portals of entry is of great interest for vaccine development against mucosal pathogens. We describe a pulmonary vaccination strategy combining Toll-like receptor (TL...

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Main Authors: Li, Adrienne Victoria (Contributor), Moon, James J. (Contributor), Abraham, Wuhbet (Contributor), Suh, Heikyung (Contributor), Elkhader, Jamal (Contributor), Seidman, Michael A. (Author), Yen, Minmin (Contributor), Im, Eung-Jun (Contributor), Foley, Maria Hottelet (Contributor), Barouch, Dan H. (Contributor), Irvine, Darrell J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Materials Science and Engineering (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2014-12-01T19:13:10Z.
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