Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells

Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells

Hundreds of chromatin regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic approach to infer CR function. We developed ChIP-string, a meso-scale assay that...

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Bibliographic Details
Main Authors: Ram, Oren (Author), Goren, Alon (Author), Amit, Ido (Author), Shoresh, Noam (Author), Yosef, Nir (Author), Ernst, Jason (Contributor), Kellis, Manolis (Contributor), Issner, Robbyn (Author), Durham, Timothy (Author), Zhang, Xiaolan (Author), Donaghey, Julie (Author), Epstein, Charles B. (Author), Regev, Aviv (Contributor), Bernstein, Bradley E. (Author), Gymrek, Melissa A. (Contributor), Coyne, Michael J. (Contributor)
Other Authors: Harvard University- (Contributor), Lincoln Laboratory (Contributor), Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-12-10T17:28:44Z.
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