Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

Electron microscopy (EM) is the standard method for imaging cellular structures with nanometer resolution, but existing genetic tags are inactive in most cellular compartments[superscript 1] or require light and can be difficult to use[superscript 2]. Here we report the development of 'APEX...

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Bibliographic Details
Main Authors: Deerinck, Thomas J. (Author), Sancak, Yasemin (Author), Poulos, Thomas L. (Author), Mootha, Vamsi K. (Author), Sosinsky, Gina E. (Author), Ellisman, Mark H. (Author), Martell, Jeffrey Daniel (Contributor), Ting, Alice Y. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2015-03-03T15:25:56Z.
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