For T Cell Receptors, Some Breakups Might Not Last Forever

For T Cell Receptors, Some Breakups Might Not Last Forever

Does the affinity or half-life of peptide-MHC-T cell receptor (TCR) interactions determine T cell activation? In this issue of Immunity, Aleksic et al. (2010) propose a role for the on rate through multiple rebindings to the same TCR.

Bibliographic Details
Main Authors: Govern, Christopher C. (Contributor), Chakraborty, Arup K. (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2015-03-19T14:43:01Z.
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