Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

The Disrupted in Schizophrenia 1 (DISC1) gene is disrupted by a balanced chromosomal translocation (1; 11) (q42; q14.3) in a Scottish family with a high incidence of major depression, schizophrenia, and bipolar disorder. Subsequent studies provided indications that DISC1 plays a role in brain develo...

Full description

Bibliographic Details
Main Authors: Mao, Yingwei (Contributor), Ge, Xuecai (Contributor), Frank, Christopher Lee (Contributor), Madison, Jon M. (Author), Koehler, Angela Nicole (Author), Doud, Mary Kathryn (Author), Tassa, Carlos (Author), Berry, Erin M. (Author), Soda, Takahiro (Contributor), Singh, Karun K. (Contributor), Biechele, Travis (Author), Petryshen, Tracey L. (Author), Moon, Randall T. (Author), Haggarty, Stephen J. (Author), Tsai, Li-Huei (Contributor)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Elsevier, 2015-03-25T16:00:37Z.
Subjects:
Online Access:Get fulltext