Loss of pRB and p107 disrupts cartilage development and promotes enchondroma formation
The pocket proteins pRB, p107 and p130 have established roles in regulating the cell cycle through the control of E2F activity. The pocket proteins regulate differentiation of a number of tissues in both cell cycle-dependent and -independent manners. Prior studies showed that mutation of p107 and p1...
Main Authors: | , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2015-04-23T15:35:41Z.
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Subjects: | |
Online Access: | Get fulltext |