HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models
The efficacy of hormonal therapies for advanced estrogen receptor-positive breast cancers is limited by the nearly inevitable development of acquired resistance. Efforts to block the emergence of resistance have met with limited success, largely because the mechanisms underlying it are so varied and...
Main Authors: | Whitesell, Luke (Author), Santagata, Sandro (Author), Mendillo, Marc L. (Author), Lin, Nancy U. (Author), Proia, David A. (Author), Lindquist, Susan (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2015-06-30T17:11:34Z.
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Subjects: | |
Online Access: | Get fulltext |
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