Implantable Silk Composite Microneedles for Programmable Vaccine Release Kinetics and Enhanced Immunogenicity in Transcutaneous Immunization
Microneedle vaccines mimic several aspects of cutaneous pathogen invasion by targeting antigen to skin-resident dendritic cells and triggering local inflammatory responses in the skin, which are correlated with enhanced immune responses. Here, we tested whether control over vaccine delivery kinetics...
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Bibliographic Details
| Main Authors: |
Min, Younjin
(Contributor),
DeMuth, Peter Charles
(Author),
Irvine, Darrell J
(Author),
Hammond, Paula T
(Author) |
|---|
| Other Authors: |
Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
(Contributor),
Massachusetts Institute of Technology. Department of Biological Engineering
(Contributor),
Massachusetts Institute of Technology. Department of Chemical Engineering
(Contributor),
Massachusetts Institute of Technology. Department of Materials Science and Engineering
(Contributor),
Ragon Institute of MGH, MIT and Harvard
(Contributor),
Koch Institute for Integrative Cancer Research at MIT
(Contributor),
DeMuth, Peter C.
(Contributor),
Irvine, Darrell J.
(Contributor),
Hammond, Paula T.
(Contributor) |
|---|
| Format: | Article
|
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| Language: | English |
|---|
| Published: |
Wiley Blackwell,
2015-10-23T17:28:23Z.
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| Subjects: | |
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| Online Access: | Get fulltext
|
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