Alteration of serum leptin and LEP/LEPR promoter methylation in Prader-Willi syndrome

Alteration of serum leptin and LEP/LEPR promoter methylation in Prader-Willi syndrome

Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder based on a loss of paternally expressed but maternally imprinted genes in chromosome region 15q11–13. PWS individuals typically show insatiable appetite with subsequent obesity representing the major mortality factor unless food intak...

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Bibliographic Details
Main Authors: Bleich, S. (Author), Buchholz, V. (Author), Deest, M. (Author), Deest-Gaubatz, S. (Author), Eberlein, C.K (Author), Frieling, H. (Author), Jahn, K. (Author), Lichtinghagen, R. (Author), Wieting, J. (Author)
Format: Article
Language:English
Published: Elsevier Ltd 2022
Subjects:
Hyperphagia
LEP
LEPR
Leptin
Methylation
Prader-Willi syndrome
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