In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde

In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde

Background: Perillaldehyde and cinnamaldehyde are natural substances found in plants that are used as flavoring ingredients. Due to the α,β-unsaturated aldehydes in their structures, these compounds are expected to be DNA reactive. Indeed, several reports have indicated that perillaldehyde and cinna...

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Bibliographic Details
Main Authors: Honma, M. (Author), Horibata, K. (Author), Masumura, K. (Author), Sugiyama, K.-I (Author), Yamada, M. (Author), Yasui, M. (Author)
Format: Article
Language:English
Published: BioMed Central Ltd 2021
Subjects:
Ames test
animal experiment
animal tissue
Article
cinnamaldehyde
Cinnamaldehyde
controlled study
ethylnitrosourea
gene mutation
gpt delta mouse
in vitro study
in vivo study
liver
male
mouse
mutagenicity
Mutagenicity
nonhuman
perillaldehyde
Perillaldehyde
quantitative structure activity relation
Quantitative structure–activity relationship
small intestine
stomach
stomach gland
Transgenic rodent gene mutation assay
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