Drug Repositioning for Fabry Disease: Acetylsalicylic Acid Potentiates the Stabilization of Lysosomal Alpha-Galactosidase by Pharmacological Chaperones

Fabry disease is caused by a deficiency of lysosomal alpha galactosidase and has a very large genotypic and phenotypic spectrum. Some patients who carry hypomorphic mutations can benefit from oral therapy with a pharmacological chaperone. The drug requires a very precise regimen because it is a reve...

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Bibliographic Details
Main Authors: Allocca, M. (Author), Andreotti, G. (Author), Bosso, A. (Author), Cubellis, M.V (Author), Liguori, L. (Author), Lukas, J. (Author), Mele, B.H (Author), Monti, M.C (Author), Monticelli, M. (Author), Morretta, E. (Author)
Format: Article
Language:English
Published: MDPI 2022
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