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1by Jingyuan Fu, Marcel G M Wolfs, Patrick Deelen, Harm-Jan Westra, Rudolf S N Fehrmann, Gerard J Te Meerman, Wim A Buurman, Sander S M Rensen, Harry J M Groen, Rinse K Weersma, Leonard H van den Berg, Jan Veldink, Roel A Ophoff, Harold Snieder, David van Heel, Ritsert C Jansen, Marten H Hofker, Cisca Wijmenga, Lude Franke“... through what mechanisms genetic variation mediate this expression. We therefore compared the cis-effect...”
Published 2012-01-01
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2by Rian M Nijmeijer, Raffaella M Gadaleta, Saskia W C van Mil, Adriaan A van Bodegraven, J Bart A Crusius, Gerard Dijkstra, Daan W Hommes, Dirk J de Jong, Pieter C F Stokkers, Hein W Verspaget, Rinse K Weersma, C Janneke van der Woude, Janneke M Stapelbroek, Marguerite E I Schipper, Cisca Wijmenga, Karel J van Erpecum, Bas Oldenburg, Dutch Initiative on Crohn, Colitis (ICC)“... genetic variation in FXR is associated with IBD. METHODS: mRNA expression of FXR and FXR target gene SHP...”
Published 2011-01-01
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3by René Luijk, Haoyu Wu, Cavin K Ward-Caviness, Eilis Hannon, Elena Carnero-Montoro, Josine L. Min, Pooja Mandaviya, Martina Müller-Nurasyid, Hailiang Mei, Silvere M. van der Maarel, BIOS Consortium, Caroline Relton, Jonathan Mill, Melanie Waldenberger, Jordana T. Bell, Rick Jansen, Alexandra Zhernakova, Lude Franke, Peter A. C. ‘t Hoen, Dorret I. Boomsma, Cornelia M. van Duijn, Marleen M. J. van Greevenbroek, Jan H. Veldink, Cisca Wijmenga, Joyce van Meurs, Lucia Daxinger, P. Eline Slagboom, Erik W. van Zwet, Bastiaan T. HeijmansGet full text
Published 2018-09-01
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4by Vinod Kumar, Harm-Jan Westra, Juha Karjalainen, Daria V Zhernakova, Tõnu Esko, Barbara Hrdlickova, Rodrigo Almeida, Alexandra Zhernakova, Eva Reinmaa, Urmo Võsa, Marten H Hofker, Rudolf S N Fehrmann, Jingyuan Fu, Sebo Withoff, Andres Metspalu, Lude Franke, Cisca Wijmenga“... in gene regulatory regions or in intergenic regions. Thus, the understanding of how genetic variations...”
Published 2013-01-01
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5by Rian M Nijmeijer, Frank G Schaap, Alexander J J Smits, Andreas E Kremer, Louis M A Akkermans, Alfons B A Kroese, Ger T Rijkers, Marguerite E I Schipper, André Verheem, Cisca Wijmenga, Hein G Gooszen, Karel J van ErpecumGet full text
Published 2014-01-01
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6by Karen M J van Loo, Tim Dejaegere, Martine van Zweeden, Jessica E van Schijndel, Cisca Wijmenga, Mieke D Trip, Gerard J M Martens“...-secretase activity in mouse embryonic fibroblasts, the genetic variation is likely functional. CONCLUSION...”
Published 2008-01-01
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7by Vasiliki Matzaraki, Vasiliki Matzaraki, Kieu T. T. Le, Martin Jaeger, Raúl Aguirre-Gamboa, Melissa D. Johnson, Serena Sanna, Diletta Rosati, Lude Franke, Alexandra Zhernakova, Jingyuan Fu, Jingyuan Fu, Sebo Withoff, Iris Jonkers, Yang Li, Yang Li, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Cisca Wijmenga, Cisca Wijmenga, Vinod Kumar, Vinod Kumar, Vinod Kumar“.... However, little is known about the genetic variation that contributes to the variability of inflammatory...”
Published 2021-08-01
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8by Adam Kiezun, Sara L Pulit, Laurent C Francioli, Freerk van Dijk, Morris Swertz, Dorret I Boomsma, Cornelia M van Duijn, P Eline Slagboom, G J B van Ommen, Cisca Wijmenga, Genome of the Netherlands Consortium, Paul I W de Bakker, Shamil R Sunyaev“...Large-scale population sequencing studies provide a complete picture of human genetic variation...”
Published 2013-01-01
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9by Firdaus A A Mohamed Hoesein, Els Wauters, Wim Janssens, Harry J M Groen, Joanna Smolonska, Cisca Wijmenga, Dirkje S Postma, H Marike Boezen, Pim A De Jong, Marc Decramer, Jan-Willem J Lammers, Diether Lambrechts, Pieter Zanen“...Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated...”
Published 2013-01-01
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10by Albertien M van Eerde, Karen Duran, Els van Riel, Carolien G F de Kovel, Bobby P C Koeleman, Nine V A M Knoers, Kirsten Y Renkema, Henricus J R van der Horst, Arend Bökenkamp, Johanna M van Hagen, Leonard H van den Berg, Katja P Wolffenbuttel, Joop van den Hoek, Wouter F Feitz, Tom P V M de Jong, Jacques C Giltay, Cisca Wijmenga“... set of 567 single nucleotide polymorphisms (SNPs) capturing their genetic variation was genotyped...”
Published 2012-01-01
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11by Rian M Nijmeijer, Hjalmar C van Santvoort, Alexandra Zhernakova, Steffen Teller, Jonas A Scheiber, Carolien G de Kovel, Marc G H Besselink, Jeroen T J Visser, Femke Lutgendorff, Thomas L Bollen, Marja A Boermeester, Ger T Rijkers, Frank U Weiss, Julia Mayerle, Markus M Lerch, Hein G Gooszen, Louis M A Akkermans, Cisca Wijmenga, Dutch Pancreatitis Study Group“... plays a role. We investigated genetic variation in MYO9B, PARD3 and MAGI2 for association with acute...”
Published 2013-01-01
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12by Jana V van Vliet-Ostaptchouk, N Charlotte Onland-Moret, Ronit Shiri-Sverdlov, Patrick J J van Gorp, Anne Custers, Petra H M Peeters, Cisca Wijmenga, Marten H Hofker, Yvonne T van der Schouw“... associated with an increased glycemic load of 1.85 units compared with non-carriers. CONCLUSIONS: Genetic...”
Published 2008-01-01
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13by Rudolf S N Fehrmann, Ritsert C Jansen, Jan H Veldink, Harm-Jan Westra, Danny Arends, Marc Jan Bonder, Jingyuan Fu, Patrick Deelen, Harry J M Groen, Asia Smolonska, Rinse K Weersma, Robert M W Hofstra, Wim A Buurman, Sander Rensen, Marcel G M Wolfs, Mathieu Platteel, Alexandra Zhernakova, Clara C Elbers, Eleanora M Festen, Gosia Trynka, Marten H Hofker, Christiaan G J Saris, Roel A Ophoff, Leonard H van den Berg, David A van Heel, Cisca Wijmenga, Gerard J Te Meerman, Lude Franke“... pharmacological intervention. Here we relied upon natural human genetic variation to identify effects...”
Published 2011-08-01
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14by Olivier B. Bakker, Aarón D. Ramírez-Sánchez, Zuzanna A. Borek, Niek de Klein, Yang Li, Rutger Modderman, Yvonne Kooy-Winkelaar, Marie K. Johannesen, Filomena Matarese, Joost H. A. Martens, Vinod Kumar, Jeroen van Bergen, Shuo-Wang Qiao, Knut E. A. Lundin, Ludvig M. Sollid, Frits Koning, Cisca Wijmenga, Sebo Withoff, Iris H. Jonkers“... receptor stimulation of gluten‑specific T cells may be impacted by genetic variation at several genetic...”
Published 2021-04-01
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15by Esteban A. Lopera Maya, Adriaan van der Graaf, Pauline Lanting, Marije van der Geest, Jingyuan Fu, Jingyuan Fu, Morris Swertz, Lude Franke, Cisca Wijmenga, Patrick Deelen, Patrick Deelen, Alexandra Zhernakova, Serena Sanna, Serena Sanna, Lifelines Cohort Study“... priming. Genetic variation in these two genes may thus modulate an individual's genetic predisposition...”
Published 2020-06-01
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