Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials

by Stephan, Matthias T., Irvine, Darrell J
Published 2015

Synergistic Antitumor Activity from Two-Stage Delivery of Targeted Toxins and Endosome-Disrupting Nanoparticles

by Su, Xingfang, Yang, Nicole Jie Yeon, Wittrup, Karl Dane, Irvine, Darrell J
Published 2013

Shaping humoral immunity to vaccines through antigen-displaying nanoparticles

by Irvine, Darrell J, Read, Benjamin J.
Published 2020

Biomaterial Strategies for Immunomodulation

by Hotaling, Nathan A., Babensee, Julia E., Tang, Li, Irvine, Darrell J
Published 2017

Engineering chemoattractant gradients using chemokine-releasing polysaccharide microspheres

by Wang, Yana, Irvine, Darrell J
Published 2015

Antigen recognition-triggered drug delivery mediated by nanocapsule-functionalized cytotoxic T-cells

by Mueller, Stephanie, Vrbanac, Vlad, Genel, Shy, Tager, Andrew M., Allen, Todd M., Jones, Richard Bradley, Kumari, Sudha, Walker, Bruce, Irvine, Darrell J
Published 2018

Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes

by Wang, Yana, Irvine, Darrell J
Published 2014

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

by Boopathy, Archana V, Tokatlian, Talar, Irvine, Darrell J
Published 2018

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine

by Moon, James J., Suh, Heikyung, Polhemus, Mark E., Ockenhouse, Christian F., Yadava, Anjali, Irvine, Darrell J
Published 2012

Synthetic Nanoparticles for Vaccines and Immunotherapy

by Rakhra, Kavya, Tokatlian, Talar, Irvine, Darrell J, Hanson, Melissa Catherine
Published 2017

Layer-by-Layer-Assembled Multilayer Films for Transcutaneous Drug and Vaccine Delivery

by Su, Xingfang, Kim, Byeong-Su, Kim, Sara R., Hammond, Paula T, Irvine, Darrell J
Published 2013

Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy

by Kwong, Brandon, Liu, Haipeng, Irvine, Darrell J
Published 2015

Design of Lipid Nanocapsule Delivery Vehicles for Multivalent Display of Recombinant Env Trimers in HIV Vaccination

by Pejawar-Gaddy, Sharmila, Kovacs, James M., Barouch, Dan H., Chen, Bing, Irvine, Darrell J
Published 2015

Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity

by Kwong, Brandon, Gai, S. Annie, Elkhader, Jamal, Wittrup, Karl Dane, Irvine, Darrell J
Published 2014

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

by Hu, Joyce K., Crampton, Jordan, Sanders, Rogier W., Moore, John P., Crotty, Shane, Tam, Hok Hei, Melo, Mariane Bandeira, Kang, Myung Sun, Pelet, Jeisa, Ruda, Vera, Foley, Maria Hottelet, Kumari, Sudha, Baldeon, Alexis D, Langer, Robert S, Anderson, Daniel Griffith, Chakraborty, Arup K, Irvine, Darrell J
Published 2017

Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells

by Abraham, Wuhbet, Zheng, Yiran, Huang, Bonnie, Bustamante Lopez, Sandra C, Irvine, Darrell J, Luo, Samantha
Published 2017

Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides

by Kim, Mikyung, Reinherz, Ellis L., Abraham, Wuhbet, Hanson, Melissa Catherine, Liu, Haipeng, Szeto, Gregory, Irvine, Darrell J, Chen, Stephanie H., Crespo, Monica P.
Published 2017

In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes

by Zheng, Yiran, Stephan, Matthias T., Gai, S. Annie, Abraham, Wuhbet, Shearer, Adrianne, Zheng, Yiran, Irvine, Darrell J
Published 2014

Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles

by Stephan, Matthias T., Stephan, Sirkka B., Bak, Peter, Chen, Jianzhu, Irvine, Darrell J
Published 2015

Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines

by Lee Szeto, Gregory, Alejandro, Brian, Park, Clara, Frew, Kirubel, Brefo, Mavis S., Mao, Shirley, Heimann, Megan, Van Egeren, Debra S., Sharei, Armon Reza, Worku, Hermoon A., Langer, Robert S, Irvine, Darrell J, Jensen, Klavs F, Szeto, Gregory
Published 2015