Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control

by Hnisz, Denes, Day, Daniel S., Young, Richard A.
Published 2018

Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

by Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y, Abraham, Brian J, Lee, Tong Ihn, Bradner, James E, Weintraub, Abraham Selby, Young, Richard A.
Published 2017

Models of human core transcriptional regulatory circuitries

by Saint-André, Violaine, Federation, Alexander J., Lin, Charles Y., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Reddy, Jessica, Young, Richard A.
Published 2017

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

by Guenther, Matthew G., Frampton, Garrett M., Soldner, Frank, Hockemeyer, Dirk, Mitalipova, Maya, Jaenisch, Rudolf, Young, Richard A.
Published 2015

Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements

by Dowen, Jill M, Bilodeau, Steve, Orlando, David A., Hübner, Michael R, Abraham, Brian J., Spector, David L, Young, Richard A, Young, Richard A.
Published 2014

The Msx1 Homeoprotein Recruits Polycomb to the Nuclear Periphery during Development

by Wang, Jingqiang, Kumar, Roshan M., Biggs, Vanessa J, Lee, Hansol, Chen, Yun, Kagey, Michael H., Young, Richard A, Abate-Shen, Cory
Published 2014

CpG island structure and trithorax/polycomb chromatin domains in human cells

by Orlando, David A., Guenther, Matthew G., Frampton, Garrett M., Young, Richard A.
Published 2016

Transcription factor trapping by RNA in gene regulatory elements

by Sigova, A. A., Abraham, B. J., Ji, X., Molinie, B., Hannett, N. M., Guo, Y. E., Giallourakis, C. C., Jangi, Mohini Rohit, Sharp, Phillip A., Young, Richard A.
Published 2017

D-Cyclins Repress Apoptosis in Hematopoietic Cells by Controlling Death Receptor Fas and Its Ligand FasL

by Choi, Yoon Jong, Saez, Borja, Anders, Lars, Hydbring, Per, Stefano, Joanna, Bacon, Nickolas A, Cook, Colleen, Kalaszczynska, Ilona, Signoretti, Sabina, Scadden, David T, Sicinski, Piotr, Young, Richard A.
Published 2017

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

by Signer, Robert A.J, Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Sonenberg, Nahum, Morrison, Sean J., Young, Richard A.
Published 2017

Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

by Dowen, Jill M, Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J, Weintraub, Abraham S, Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Zhang, Lyndon Nuoxi, Young, Richard A.
Published 2016

Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes

by Cheng, Bo, Li, Tiandao, Rahl, Peter B, Adamson, Todd E, Loudas, Nicholas B, Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J, Hu, Xiaopeng, Gnatt, Averell, Price, David H, Young, Richard A.
Published 2018

Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

by Fulciniti, Mariateresa, Lin, Charles Y., Samur, Mehmet K., Lopez, Michael A., Singh, Irtisha, Lawlor, Matthew A., Szalat, Raphael E., Ott, Christopher J., Avet-Loiseau, Herve', Anderson, Kenneth C., Young, Richard A., Bradner, James E., Munshi, Nikhil C.
Published 2020

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

by Durbin, Adam D., Abraham, Brian J., Lawton, Lee N., Young, Richard A., Sanda, Takaomi
Published 2020

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

by Juan, Aster H., Kumar, Roshan M., Marx, Joseph G., Young, Richard A., Sartorelli, Vittorio
Published 2012

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry

by Abraham, Brian J., Young, Richard A.
Published 2020

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

by Whyte, Warren A, Orlando, David A, Hnisz, Denes, Abraham, Brian J, Lin, Charles Y, Kagey, Michael H, Rahl, Peter B, Lee, Tong Ihn, Young, Richard A, Young, Richard A.
Published 2016

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

by Almada, Albert Ernesto, Lin, Charles, Sharp, Phillip A., Young, Richard A., Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Giallourakis, Cosmas C.
Published 2013

BET bromodomain proteins regulate enhancer function during adipogenesis

by Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Plutzky, Jorge, Bradner, James E., Young, Richard A.
Published 2018

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

by D'Alessio, Ana C, Fan, Zi Peng, Wert, Katherine J, Baranov, Petr, Cohen, Malkiel A, Saini, Janmeet S, Cohick, Evan, Charniga, Carol, Hannett, Nancy M, Young, Michael J, Temple, Sally, Jaenisch, Rudolf, Lee, Tong Ihn, Young, Richard A, Dadon, Daniel Benjamin, Young, Richard A.
Published 2016