SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells

by Hedia Chagraoui, Maiken S. Kristiansen, Juan Pablo Ruiz, Ana Serra-Barros, Johanna Richter, Elisa Hall-Ponselé, Nicki Gray, Dominic Waithe, Kevin Clark, Philip Hublitz, Emmanouela Repapi, Georg Otto, Paul Sopp, Stephen Taylor, Supat Thongjuea, Paresh Vyas, Catherine Porcher
Published 2018-12-01

New challenges in diagnosis of haemoglobinopathies: Migration of populations

by John Old, Adele Timbs, Janice McCarthy, Alice Gallienne, Melanie Proven, Michelle Rugless, Herminio Lopez, Jennifer Eglinton, Dariusz Dziedzic, Matthew Beardsall, Mohamed S.M. Khalila, Shirley Henderson
Published 2018-04-01

Insights into pancreatic β cell energy metabolism using rodent β cell models [version 3; peer review: 2 approved, 1 not approved]

by Karl J Morten, Michelle Potter, Luned Badder, Pamela Sivathondan, Rebecca Dragovic, Abigale Neumann, James Gavin, Roshan Shrestha, Svetlana Reilly, Kanchan Phadwal, Tiffany A. Lodge, Angela Borzychowski, Sharon Cookson, Corey Mitchell, Alireza Morovat, Anna Katharina Simon, Johanna Uusimaa, James Hynes, Joanna Poulton
Published 2019-09-01

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

by Amit Grover, Alejandra Sanjuan-Pla, Supat Thongjuea, Joana Carrelha, Alice Giustacchini, Adriana Gambardella, Iain Macaulay, Elena Mancini, Tiago C. Luis, Adam Mead, Sten Eirik W. Jacobsen, Claus Nerlov
Published 2016-03-01

Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium

by Florian Bonkhofer, Rossella Rispoli, Philip Pinheiro, Monika Krecsmarik, Janina Schneider-Swales, Ingrid Ho Ching Tsang, Marella de Bruijn, Rui Monteiro, Tessa Peterkin, Roger Patient
Published 2019-08-01

NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses

by Daniele Corridoni, Daniele Corridoni, Seiji Shiraishi, Seiji Shiraishi, Thomas Chapman, Thomas Chapman, Tessa Steevels, Tessa Steevels, Daniele Muraro, Daniele Muraro, Marie-Laëtitia Thézénas, Gennaro Prota, Ji-Li Chen, Uzi Gileadi, Nicola Ternette, Vincenzo Cerundolo, Alison Simmons, Alison Simmons
Published 2019-04-01

Total Mapping Toolbox (TOMATO): An open source library for cardiac magnetic resonance parametric mapping

by Konrad Werys, Iulius Dragonu, Qiang Zhang, Iulia Popescu, Evan Hann, Henrike Puchta, Agata Kubik, Dogan Polat, Cody Wu, Niall O. Moon, Ahmet Barutcu, Vanessa M. Ferreira, Stefan K. Piechnik
Published 2020-01-01

SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus [version 2; peer review: 2 approved]

by Monique I. Andersson, Carolina V. Arancibia-Carcamo, Kathryn Auckland, J. Kenneth Baillie, Eleanor Barnes, Tom Beneke, Sagida Bibi, Tim Brooks, Miles Carroll, Derrick Crook, Kate Dingle, Christina Dold, Louise O. Downs, Laura Dunn, David W. Eyre, Javier Gilbert Jaramillo, Heli Harvala, Sarah Hoosdally, Samreen Ijaz, Tim James, William James, Katie Jeffery, Anita Justice, Paul Klenerman, Julian C. Knight, Michael Knight, Xu Liu, Sheila F. Lumley, Philippa C. Matthews, Anna L. McNaughton, Alexander J. Mentzer, Juthathip Mongkolsapaya, Sarah Oakley, Marta S. Oliveira, Timothy Peto, Rutger J. Ploeg, Jeremy Ratcliff, Melanie J. Robbins, David J. Roberts, Justine Rudkin, Rebecca A. Russell, Gavin Screaton, Malcolm G. Semple, Donal Skelly, Peter Simmonds, Nicole Stoesser, Lance Turtle, Susan Wareing, Maria Zambon
Published 2020-10-01

Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing

by Simona Valletta, Alexander Thomas, Yiran Meng, Xiying Ren, Roy Drissen, Hilal Sengül, Cristina Di Genua, Claus Nerlov
Published 2020-08-01

A haemagglutination test for rapid detection of antibodies to SARS-CoV-2

by Alain Townsend, Pramila Rijal, Julie Xiao, Tiong Kit Tan, Kuan-Ying A. Huang, Lisa Schimanski, Jiandong Huo, Nimesh Gupta, Rolle Rahikainen, Philippa C. Matthews, Derrick Crook, Sarah Hoosdally, Susanna Dunachie, Eleanor Barnes, Teresa Street, Christopher P. Conlon, John Frater, Carolina V. Arancibia-Cárcamo, Justine Rudkin, Nicole Stoesser, Fredrik Karpe, Matthew Neville, Rutger Ploeg, Marta Oliveira, David J. Roberts, Abigail A. Lamikanra, Hoi Pat Tsang, Abbie Bown, Richard Vipond, Alexander J. Mentzer, Julian C. Knight, Andrew J. Kwok, Gavin R. Screaton, Juthathip Mongkolsapaya, Wanwisa Dejnirattisai, Piyada Supasa, Paul Klenerman, Christina Dold, J. Kenneth Baillie, Shona C. Moore, Peter J. M. Openshaw, Malcolm G. Semple, Lance C. W. Turtle, Mark Ainsworth, Alice Allcock, Sally Beer, Sagida Bibi, Donal Skelly, Lizzy Stafford, Katie Jeffrey, Denise O’Donnell, Elizabeth Clutterbuck, Alexis Espinosa, Maria Mendoza, Dominique Georgiou, Teresa Lockett, Jose Martinez, Elena Perez, Veronica Gallardo Sanchez, Giuseppe Scozzafava, Alberto Sobrinodiaz, Hannah Thraves, Etienne Joly
Published 2021-03-01

Effect of glycaemic control on complications following cardiac surgery: literature review

by M. Navaratnarajah, R. Rea, R. Evans, F. Gibson, C. Antoniades, A. Keiralla, M. Demosthenous, G. Kassimis, G. Krasopoulos
Published 2018-01-01

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion

by Mandeep S. Singh, Jasmin Balmer, Alun R. Barnard, Sher A. Aslam, Daniela Moralli, Catherine M. Green, Alona Barnea-Cramer, Isabel Duncan, Robert E. MacLaren
Published 2016-11-01

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks

by Ann-Marie K. Shorrocks, Samuel E. Jones, Kaima Tsukada, Carl A. Morrow, Zoulikha Belblidia, Johanna Shen, Iolanda Vendrell, Roman Fischer, Benedikt M. Kessler, Andrew N. Blackford
Published 2021-01-01

Emerging Mechanisms of Innate Immunity and Their Translational Potential in Inflammatory Bowel Disease

by Daniele Corridoni, Daniele Corridoni, Thomas Chapman, Thomas Chapman, Tim Ambrose, Tim Ambrose, Alison Simmons, Alison Simmons
Published 2018-02-01

Autophagy is a critical regulator of memory CD8+ T cell formation

by Daniel J Puleston, Hanlin Zhang, Timothy J Powell, Elina Lipina, Stuart Sims, Isabel Panse, Alexander S Watson, Vincenzo Cerundolo, Alain RM Townsend, Paul Klenerman, Anna Katharina Simon
Published 2014-11-01

Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors

by Chloe H. Lee, Chloe H. Lee, Mariolina Salio, Giorgio Napolitani, Graham Ogg, Alison Simmons, Alison Simmons, Hashem Koohy, Hashem Koohy
Published 2020-10-01

T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine

by Thomas Krausgruber, Chris Schiering, Krista Adelmann, Oliver J. Harrison, Agnieszka Chomka, Claire Pearson, Philip P. Ahern, Matthew Shale, Mohamed Oukka, Fiona Powrie
Published 2016-05-01

The interplay between metabolic alterations, diastolic strain rate and exercise capacity in mild heart failure with preserved ejection fraction: a cardiovascular magnetic resonance...

by Masliza Mahmod, Nikhil Pal, Jennifer Rayner, Cameron Holloway, Betty Raman, Sairia Dass, Eylem Levelt, Rina Ariga, Vanessa Ferreira, Rajarshi Banerjee, Jurgen E. Schneider, Christopher Rodgers, Jane M. Francis, Theodoros D. Karamitsos, Michael Frenneaux, Houman Ashrafian, Stefan Neubauer, Oliver Rider
Published 2018-12-01

Oscillatory neural representations in the thalamus predict neuropathic pain relief by deep brain stimulation

by Y. Huang, A. Green, J. Hyam, J. Fitzgerald, T. Aziz, S. Wang
Published 2017-03-01

Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells

by Masahiro Kawashima, Karim Bensaad, Christos E. Zois, Alessandro Barberis, Esther Bridges, Simon Wigfield, Christoffer Lagerholm, Ruslan I. Dmitriev, Mariko Tokiwa, Masakazu Toi, Dmitri B. Papkovsky, Francesca M. Buffa, Adrian L. Harris
Published 2020-08-01