Cluster Analysis of Dry Eye Disease Models Based on Immune Cell Parameters – New Insight Into Therapeutic Perspective

by Chit Tong Lio, Sandeep Kumar Dhanda, Tanima Bose
Published 2020-09-01

Rapid Induction and Maintenance of Virus-Specific CD8+ TEMRA and CD4+ TEM Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans

by Nancy Graham, Nancy Graham, Phil Eisenhauer, Phil Eisenhauer, Sean A. Diehl, Sean A. Diehl, Kristen K. Pierce, Kristen K. Pierce, Stephen S. Whitehead, Anna P. Durbin, Beth D. Kirkpatrick, Beth D. Kirkpatrick, Beth D. Kirkpatrick, Alessandro Sette, Alessandro Sette, Daniela Weiskopf, Jonathan E. Boyson, Jason W. Botten, Jason W. Botten, Jason W. Botten
Published 2020-03-01

AI-guided discovery of the invariant host response to viral pandemics

by Debashis Sahoo, Gajanan D. Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire, Vanessa Castillo, Courtney Tindle, MacKenzie Fuller, Sahar Taheri, Thomas F. Rogers, Nathan Beutler, Sydney I. Ramirez, Stephen A. Rawlings, Victor Pretorius, Davey M. Smith, Dennis R. Burton, Laura E. Crotty Alexander, Jason Duran, Shane Crotty, Jennifer M. Dan, Soumita Das, Pradipta Ghosh
Published 2021-06-01

An Overview of Vaccines against SARS-CoV-2 in the COVID-19 Pandemic Era

by Alejandro Pascual-Iglesias, Javier Canton, Ana Maria Ortega-Prieto, Jose M. Jimenez-Guardeño, Jose Angel Regla-Nava
Published 2021-08-01

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

by Renée J. H. A. Tillie, Jenny De Bruijn, Javier Perales-Patón, Javier Perales-Patón, Lieve Temmerman, Yanal Ghosheh, Kim Van Kuijk, Marion J. Gijbels, Marion J. Gijbels, Marion J. Gijbels, Peter Carmeliet, Peter Carmeliet, Peter Carmeliet, Klaus Ley, Klaus Ley, Julio Saez-Rodriguez, Julio Saez-Rodriguez, Judith C. Sluimer, Judith C. Sluimer
Published 2021-08-01

Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity

by Valerie Sapp, Aitor Aguirre, Gayatri Mainkar, Jeffrey Ding, Eric Adler, Ronglih Liao, Sonia Sharma, Mohit Jain
Published 2021-07-01

Host Immune-Metabolic Adaptations Upon Mycobacterial Infections and Associated Co-Morbidities

by Alba Llibre, Martin Dedicoat, Julie G. Burel, Caroline Demangel, Matthew K. O’Shea, Matthew K. O’Shea, Claudio Mauro
Published 2021-09-01

Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube

by Huy Q. Dinh, Xianzhi Lin, Forough Abbasi, Robbin Nameki, Marcela Haro, Claire E. Olingy, Heidi Chang, Lourdes Hernandez, Simon A. Gayther, Kelly N. Wright, Paul-Joseph Aspuria, Beth Y. Karlan, Rosario I. Corona, Andrew Li, B.J. Rimel, Matthew T. Siedhoff, Fabiola Medeiros, Kate Lawrenson
Published 2021-04-01

Time elapsed between Zika and dengue virus infections affects antibody and T cell responses

by Erick X. Pérez-Guzmán, Petraleigh Pantoja, Crisanta Serrano-Collazo, Mariah A. Hassert, Alexandra Ortiz-Rosa, Idia V. Rodríguez, Luis Giavedoni, Vida Hodara, Laura Parodi, Lorna Cruz, Teresa Arana, Laura J. White, Melween I. Martínez, Daniela Weiskopf, James D. Brien, Aravinda de Silva, Amelia K. Pinto, Carlos A. Sariol
Published 2019-09-01

Analysis of human mitochondrial genome co-occurrence networks of Asian population at varying altitudes

by Rahul K. Verma, Alena Kalyakulina, Cristina Giuliani, Pramod Shinde, Ajay Deep Kachhvah, Mikhail Ivanchenko, Sarika Jalan
Published 2021-01-01

Molecular Characterization of the Native (Non-Linked) CD160–HVEM Protein Complex Revealed by Initial Crystallographic Analysis

by Simona Lenhartová, Marek Nemčovič, Radka Šebová, Mário Benko, Dirk M. Zajonc, Ivana Nemčovičová
Published 2021-07-01

Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals

by Norihide Jo, Norihide Jo, Rui Zhang, Hideki Ueno, Hideki Ueno, Takuya Yamamoto, Takuya Yamamoto, Daniela Weiskopf, Miki Nagao, Shinya Yamanaka, Shinya Yamanaka, Yoko Hamazaki, Yoko Hamazaki
Published 2021-08-01

Emergence of a Novel Dengue Virus 3 (DENV-3) Genotype-I Coincident with Increased DENV-3 Cases in Yangon, Myanmar between 2017 and 2019

by Aung Min Soe, Mya Myat Ngwe Tun, Takeshi Nabeshima, Theingi Win Myat, Moh Moh Htun, Htin Lin, Nang Sarm Hom, Shingo Inoue, Khine Mya Nwe, Lynn Pa Pa Aye, Mizuki Fukuta, Kyaw Zin Thant, Futoshi Hasebe, Kouichi Morita, Sujan Shresta, Hlaing Myat Thu, Meng Ling Moi
Published 2021-06-01

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

by Ane Ogbe, Barbara Kronsteiner, Donal T. Skelly, Matthew Pace, Anthony Brown, Emily Adland, Kareena Adair, Hossain Delowar Akhter, Mohammad Ali, Serat-E Ali, Adrienn Angyal, M. Azim Ansari, Carolina V. Arancibia-Cárcamo, Helen Brown, Senthil Chinnakannan, Christopher Conlon, Catherine de Lara, Thushan de Silva, Christina Dold, Tao Dong, Timothy Donnison, David Eyre, Amy Flaxman, Helen Fletcher, Joshua Gardner, James T. Grist, Carl-Philipp Hackstein, Kanoot Jaruthamsophon, Katie Jeffery, Teresa Lambe, Lian Lee, Wenqin Li, Nicholas Lim, Philippa C. Matthews, Alexander J. Mentzer, Shona C. Moore, Dean J. Naisbitt, Monday Ogese, Graham Ogg, Peter Openshaw, Munir Pirmohamed, Andrew J. Pollard, Narayan Ramamurthy, Patpong Rongkard, Sarah Rowland-Jones, Oliver Sampson, Gavin Screaton, Alessandro Sette, Lizzie Stafford, Craig Thompson, Paul J. Thomson, Ryan Thwaites, Vinicius Vieira, Daniela Weiskopf, Panagiota Zacharopoulou, Oxford Immunology Network Covid-19 Response T Cell Consortium, Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team, Lance Turtle, Paul Klenerman, Philip Goulder, John Frater, Eleanor Barnes, Susanna Dunachie
Published 2021-04-01

An in silico—in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

by Michele Mishto, Michele Mishto, Artem Mansurkhodzhaev, Ge Ying, Aruna Bitra, Robert A. Cordfunke, Sarah Henze, Debdas Paul, John Sidney, Henning Urlaub, Henning Urlaub, Jacques Neefjes, Alessandro Sette, Alessandro Sette, Dirk M. Zajonc, Dirk M. Zajonc, Juliane Liepe, Juliane Liepe
Published 2019-11-01

Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM

by Aleksandar Antanasijevic, Leigh M. Sewall, Christopher A. Cottrell, Diane G. Carnathan, Luis E. Jimenez, Julia T. Ngo, Jennifer B. Silverman, Bettina Groschel, Erik Georgeson, Jinal Bhiman, Raiza Bastidas, Celia LaBranche, Joel D. Allen, Jeffrey Copps, Hailee R. Perrett, Kimmo Rantalainen, Fabien Cannac, Yuhe R. Yang, Alba Torrents de la Peña, Rebeca Froes Rocha, Zachary T. Berndsen, David Baker, Neil P. King, Rogier W. Sanders, John P. Moore, Shane Crotty, Max Crispin, David C. Montefiori, Dennis R. Burton, William R. Schief, Guido Silvestri, Andrew B. Ward
Published 2021-08-01

Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

by In-San Kim, Chang-Yuil Kang, Jeong Uk Choi, Na Kyeong Lee, Hyungseok Seo, Seung Woo Chung, Taslim A Al-Hilal, Seong Jin Park, Seho Kweon, Nuri Min, Sang Kyoon Kim, Seohyun Ahn, Uk-Il Kim, Jin Woo Park, Sang Yoon Kim, Kyungjin Kim, Youngro Byun
Published 2021-08-01

The ADC API: A Web API for the Programmatic Query of the AIRR Data Commons

by Scott Christley, Ademar Aguiar, Ademar Aguiar, George Blanck, Felix Breden, Syed Ahmad Chan Bukhari, Christian E. Busse, Jerome Jaglale, Srilakshmy L. Harikrishnan, Uri Laserson, Bjoern Peters, Bjoern Peters, Artur Rocha, Chaim A. Schramm, Sarah Taylor, Jason Anthony Vander Heiden, Bojan Zimonja, Corey T. Watson, Brian Corrie, Lindsay G. Cowell
Published 2020-06-01

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

by Yujiao He, Zhiguo Yang, Chen-si Zhao, Zhihui Xiao, Yu Gong, Yun-Yi Li, Yiqi Chen, Yunting Du, Dianying Feng, Amnon Altman, Yingqiu Li
Published 2021-06-01

Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

by Pavlo Gilchuk, Adrian Guthals, Stefano R. Bonissone, Jared B. Shaw, Philipp A. Ilinykh, Philipp A. Ilinykh, Kai Huang, Kai Huang, Robin G. Bombardi, Jenny Liang, Ariadna Grinyo, Edgar Davidson, Elaine C. Chen, Bronwyn M. Gunn, Galit Alter, Erica Ollmann Saphire, Benjamin J. Doranz, Alexander Bukreyev, Alexander Bukreyev, Alexander Bukreyev, Larry Zeitlin, Natalie Castellana, James E. Crowe, James E. Crowe, James E. Crowe
Published 2021-07-01