Showing 61 - 80 results of 140 for search '"PSEN2"', query time: 1.85s Refine Results
  1. 61
    A Pathogenic Variant p.Phe177Val in PSEN1 Causes Early-Onset Alzheimer’s Disease in a Chinese Family
    “... in the genes encoding for amyloid precursor protein (APP), presenilin-1 (PSEN1), and presenilin-2 (PSEN2...”
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    Article
  2. 62
    The Genetics of Alzheimer’s Disease
    by Robert C. Barber
    Published 2012-01-01
    “... in Mendelian dominant fashion and is caused by mutations in three genes (APP, PSEN1, and PSEN2). Late onset...”
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    Article
  3. 63
    Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD
    by Suzanne Elizabeth Schindler, Anne M Fagan
    Published 2015-06-01
    “... in the genes coding for Amyloid Precursor Protein (APP), Presenilin 1 (PSEN-1) and Presenilin 2 (PSEN-2) cause...”
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    Article
  4. 64
    Generation of two iPSC lines with either a heterozygous V717I or a heterozygous KM670/671NL mutation in the APP gene
    “... worldwide. Mutations in the genes PSEN1, PSEN2 or APP are known to cause familial forms of AD with an early...”
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    Article
  5. 65
    Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
    “... mutation in PSEN2. The generated iPSC colonies grew and were characterized by pluripotency marker staining...”
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    Article
  6. 66
    Nuevos genes descubiertos relacionados con la Enfermedad de Alzheimer
    “... y signos de la enfermedad. Entre ellos están los genes ya conocidos APP, PSEN1 y PSEN2. Con los...”
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    Article
  7. 67
    The hypothesis that Helicobacter pylori predisposes to Alzheimer’s disease is biologically plausible
    “... the hallmarks of Alzheimer’s disease: APP, APOE, PSEN1, and PSEN2. A large fraction of modulated genes (30 out...”
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    Article
  8. 68
    Genes associated with Alzheimer's disease: an overview and current status
    by Giri M, Zhang M, Lü Y
    Published 2016-05-01
    “.... Linkage analysis was the first milestone in unraveling the mutations in APP, PSEN1, and PSEN2 that cause...”
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    Article
  9. 69
    Genetics of Early-Onset Alzheimer Dementia
    “...), presenilin 1 (PSEN1) and presenilin 2 (PSEN2). PSEN1 is the most frequently mutated EOAD gene with a mutation...”
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    Article
  10. 70
    Genetic of Alzheimer's Disease: A Narrative Review Article
    “.... In this form, dominant mutations in genes like APP, PSEN-1 and PSEN-2 associated with AD. This study aimed...”
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    Article
  11. 71
    Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
    by Toshifumi Nomura
    Published 2020-05-01
    “.... Furthermore, Psen1–/Psen2–, Psen1–, Ncstn+/–, and Notch1–/Notch2– mice share common phenotypes of human HS...”
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    Article
  12. 72
    The Genetics of Alzheimer’s Disease in the Chinese Population
    by Chen-Ling Gan, Tao Zhang, Tae Ho Lee
    Published 2020-03-01
    “.... This review summarizes three early-onset AD causative genes (<i>APP</i>, <i>PSEN1</i>, and <i>PSEN2</i...”
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    Article
  13. 73
    Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites.
    “.../presenilin2 (Psen1/Psen2), and by pharmacological blocking of the Notch pathway. In contrast to the fish...”
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    Article
  14. 74
    Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2
    “... (<i>APP</i>), presenilin-1 (<i>PSEN1</i>), and presenilin-2 (<i>PSEN2</i>) genes. AD mutations...”
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    Article
  15. 75
    Genetic architecture of Alzheimer's disease
    by Sarah M. Neuner, Julia TCW, Alison M. Goate
    Published 2020-09-01
    “...1, PSEN2, and APOE have been shown to exhibit large effects on disease susceptibility...”
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    Article
  16. 76
    Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases
    by Mark Preciados, Changwon Yoo, Deodutta Roy
    Published 2016-12-01
    “...1B, MAPT, PSEN2 and TNF—underlie the enrichment of the Kyoto Encyclopedia of Genes and Genomes (KEGG...”
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    Article
  17. 77
    Modeling Alzheimer’s Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
    by Weiwei Zhang, Bin Jiao, Miaojin Zhou, Tao Zhou, Lu Shen
    Published 2016-01-01
    “..., and PSEN2), the ultimate cause behind the rest of the cases, called sporadic AD, remains unknown. Current...”
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    Article
  18. 78
    Association of a BACE1 Gene Polymorphism with Parkinson’s Disease in a Norwegian Population
    “... was to investigate whether candidate polymorphisms in five genes (ADAM10, BACE1, BACE2, PSEN2, and CLU) involved...”
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    Article
  19. 79
    Measures of onset, progression and intervention in Alzheimer's disease : the familial paradigm
    by Knight, W. D.
    Published 2010
    “... (PSEN2) gene mutations permit both, and therefore lend themselves to clinical research with results...”
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  20. 80
    Presenilin mutations and their impact on neuronal differentiation in Alzheimer’s disease
    “...The presenilin genes (PSEN1 and PSEN2) are mainly responsible for causing early-onset familial...”
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    Article
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