A Novel Aurora Kinase Inhibitor Attenuates Leukemic Cell Proliferation Induced by Mesenchymal Stem Cells

by Jun-Dan Wang, Wei Zhang, Jing-Wen Zhang, Ling Zhang, Le-Xun Wang, Hong-Sheng Zhou, Liang Long, Gui Lu, Quentin Liu, Zi-Jie Long
Published 2020-09-01

A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer

by Jennifer R. Diamond, S. G. Eckhardt, Todd M. Pitts, Adrie van Bokhoven, Dara Aisner, Daniel L. Gustafson, Anna Capasso, Sharon Sams, Peter Kabos, Kathryn Zolman, Tiffany Colvin, Anthony D. Elias, Anna M. Storniolo, Bryan P. Schneider, Dexiang Gao, John J. Tentler, Virginia F. Borges, Kathy D. Miller
Published 2018-08-01

Corrigendum: Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells

by Yanfang Li, Tao Liu, Cristina Ivan, Cristina Ivan, Jie Huang, De-Yu Shen, John J. Kavanagh, Robert C. Bast, Siqing Fu, Wei Hu, Anil K. Sood, Anil K. Sood, Anil K. Sood
Published 2018-02-01

Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells

by Yanfang Li, Tao Liu, Cristina Ivan, Cristina Ivan, Jie Huang, De-Yu Shen, John J. Kavanagh, Robert C. Bast, Siqing Fu, Wei Hu, Anil K. Sood, Anil K. Sood, Anil K. Sood
Published 2013-03-01

Elevated ABCB1 Expression Confers Acquired Resistance to Aurora Kinase Inhibitor GSK-1070916 in Cancer Cells

by Zhuo-Xun Wu, Yuqi Yang, Jing-Quan Wang, Wen-Min Zhou, Junyu Chen, Yi-Ge Fu, Ketankumar Patel, Zhe-Sheng Chen, Jian-Ye Zhang
Published 2021-01-01

Overexpression of human ATP-binding cassette transporter ABCG2 contributes to reducing the cytotoxicity of GSK1070916 in cancer cells

by Zhuo-Xun Wu, Qiuyan Mai, Yuqi Yang, Jing-Quan Wang, Hansu Ma, Leli Zeng, Zhe-Sheng Chen, Yihang Pan
Published 2021-04-01

Aurora kinase inhibitors: which role in the treatment of chronic myelogenous leukemia patients resistant to imatinib?

by Giovanni Martinelli, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Daniela Cilloni, Michele Baccarani
Published 2009-02-01

Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

by Siggelkow Wulf, Boehm Daniel, Gebhard Susanne, Battista Marco, Sicking Isabel, Lebrecht Antje, Solbach Christine, Hellwig Birte, Rahnenführer Jörg, Koelbl Heinz, Gehrmann Mathias, Marchan Rosemarie, Cadenas Cristina, Hengstler Jan G, Schmidt Marcus
Published 2012-11-01

Design, synthesis and biological activity of N4-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kin...

by Sonali Kurup, Bradley McAllister, Pavlina Liskova, Trusha Mistry, Anthony Fanizza, Dan Stanford, Jolanta Slawska, Ulrich Keller, Alexander Hoellein
Published 2018-01-01