Population-level distribution and putative immunogenicity of cancer neoepitopes

by Mary A. Wood, Mayur Paralkar, Mihir P. Paralkar, Austin Nguyen, Adam J. Struck, Kyle Ellrott, Adam Margolin, Abhinav Nellore, Reid F. Thompson
Published 2018-04-01

Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer

by Apostolos Zaravinos, Constantinos Roufas, Majdi Nagara, Beatriz de Lucas Moreno, Maria Oblovatskaya, Christodoulos Efstathiades, Christos Dimopoulos, Georgios D. Ayiomamitis
Published 2019-08-01

Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery

by Eric de Sousa, Joana R. Lérias, Antonio Beltran, Georgia Paraschoudi, Carolina Condeço, Jéssica Kamiki, Patrícia Alexandra António, Nuno Figueiredo, Carlos Carvalho, Mireia Castillo-Martin, Zhe Wang, Dário Ligeiro, Martin Rao, Markus Maeurer, Markus Maeurer
Published 2021-07-01

An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes

by Anne-Mette Bjerregaard, Morten Nielsen, Morten Nielsen, Vanessa Jurtz, Carolina M. Barra, Sine Reker Hadrup, Zoltan Szallasi, Zoltan Szallasi, Aron Charles Eklund
Published 2017-11-01

Corrigendum: An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes

by Anne-Mette Bjerregaard, Morten Nielsen, Morten Nielsen, Vanessa Jurtz, Carolina M. Barra, Sine Reker Hadrup, Zoltan Szallasi, Zoltan Szallasi, Aron Charles Eklund
Published 2018-05-01

Combining Photodynamic Therapy with Immunostimulatory Nanoparticles Elicits Effective Anti-Tumor Immune Responses in Preclinical Murine Models

by Ruben Victor Huis in ‘t Veld, Candido G. Da Silva, Martine J. Jager, Luis J. Cruz, Ferry Ossendorp
Published 2021-09-01

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display

by Stina L. Wickström, Tanja Lövgren, Tanja Lövgren, Michael Volkmar, Bruce Reinhold, Bruce Reinhold, Jonathan S. Duke-Cohan, Jonathan S. Duke-Cohan, Laura Hartmann, Janina Rebmann, Anja Mueller, Jeroen Melief, Roeltje Maas, Maarten Ligtenberg, Johan Hansson, Rienk Offringa, Barbara Seliger, Isabel Poschke, Isabel Poschke, Ellis L. Reinherz, Ellis L. Reinherz, Rolf Kiessling
Published 2019-12-01

Tumor-Infiltrating T Cells From Clear Cell Renal Cell Carcinoma Patients Recognize Neoepitopes Derived From Point and Frameshift Mutations

by Ulla Kring Hansen, Sofie Ramskov, Anne-Mette Bjerregaard, Annie Borch, Rikke Andersen, Arianna Draghi, Marco Donia, Amalie Kai Bentzen, Andrea Marion Marquard, Zoltan Szallasi, Aron Charles Eklund, Aron Charles Eklund, Inge Marie Svane, Sine Reker Hadrup
Published 2020-03-01

Neoepitopes in Type 1 Diabetes: Etiological Insights, Biomarkers and Therapeutic Targets

by Teresa Rodriguez-Calvo, James D. Johnson, Lut Overbergh, Jessica L. Dunne
Published 2021-04-01

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

by Sefina Arif, Irma Pujol-Autonell, Yogesh Kamra, Evangelia Williams, Norkhairin Yusuf, Clara Domingo-Vila, Yasaman Shahrabi, Emily Pollock, Leena Khatri, Mark Peakman, Timothy Tree, Anna Lorenc
Published 2021-06-01

Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival

by Mary A. Wood, Benjamin R. Weeder, Julianne K. David, Abhinav Nellore, Reid F. Thompson
Published 2020-03-01

The Potential and Challenges of Exploiting the Vast But Dynamic Neoepitope Landscape for Immunotherapy

by Els M. E. Verdegaal, Sjoerd H. van der Burg
Published 2017-09-01

Citrullination and PAD Enzyme Biology in Type 1 Diabetes – Regulators of Inflammation, Autoimmunity, and Pathology

by Mei-Ling Yang, Fernanda M. C. Sodré, Mark J. Mamula, Lut Overbergh
Published 2021-06-01

Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome

by Luis Zapata, Oriol Pich, Luis Serrano, Fyodor A. Kondrashov, Stephan Ossowski, Martin H. Schaefer
Published 2018-05-01

A non-functional neoepitope specific CD8+ T-cell response induced by tumor derived antigen exposure in vivo

by Mathias Vormehr, Katharina Reinhard, Renata Blatnik, Kathrin Josef, Jan David Beck, Nadja Salomon, Martin Suchan, Abderraouf Selmi, Fulvia Vascotto, Johannes Zerweck, Holger Wenschuh, Mustafa Diken, Sebastian Kreiter, Özlem Türeci, Angelika B. Riemer, Ugur Sahin
Published 2019-03-01

A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations

by Jugmohit S. Toor, Arjun A. Rao, Andrew C. McShan, Mark Yarmarkovich, Santrupti Nerli, Santrupti Nerli, Karissa Yamaguchi, Ada A. Madejska, Son Nguyen, Sarvind Tripathi, John M. Maris, Sofie R. Salama, Sofie R. Salama, David Haussler, David Haussler, Nikolaos G. Sgourakis
Published 2018-01-01

Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells

by W Richter, B Moradi, CB Little, J Fischer, S Boeuf, F Graf
Published 2012-05-01

Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles

by Alberto Grandi, Michele Tomasi, Ilaria Zanella, Luisa Ganfini, Elena Caproni, Laura Fantappiè, Carmela Irene, Luca Frattini, Samine J. Isaac, Enrico König, Francesca Zerbini, Simona Tavarini, Chiara Sammicheli, Fabiola Giusti, Ilaria Ferlenghi, Matteo Parri, Guido Grandi
Published 2017-11-01

Predicting T cell recognition of MHC class I restricted neoepitopes

by Zeynep Koşaloğlu-Yalçın, Manasa Lanka, Angela Frentzen, Ashmitaa Logandha Ramamoorthy Premlal, John Sidney, Kerrie Vaughan, Jason Greenbaum, Paul Robbins, Jared Gartner, Alessandro Sette, Bjoern Peters
Published 2018-11-01

ProTECT—Prediction of T-Cell Epitopes for Cancer Therapy

by Arjun A. Rao, Arjun A. Rao, Arjun A. Rao, Ada A. Madejska, Ada A. Madejska, Jacob Pfeil, Jacob Pfeil, Jacob Pfeil, Benedict Paten, Benedict Paten, Benedict Paten, Sofie R. Salama, Sofie R. Salama, Sofie R. Salama, David Haussler, David Haussler, David Haussler, David Haussler
Published 2020-11-01