Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

by Yue Shen, Matthew R. Zeglinski, Christopher T. Turner, Sheetal A. Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R. Cameron, Anthony Papp, David J. Granville
Published 2018-05-01

Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering

by Yeonsue Jang, Jinhyeok Choi, Narae Park, Jaewoo Kang, Myungshin Kim, Yonggoo Kim, Ji Hyeon Ju
Published 2019-01-01

Heteromerization of μ-opioid receptor and cholecystokinin B receptor through the third transmembrane domain of the μ-opioid receptor contributes to the anti-opioid effects of chole...

by Yin Yang, Qian Li, Qi-Hua He, Ji-Sheng Han, Li Su, You Wan
Published 2018-05-01

Recent advances in cancer metabolism: a technological perspective

by Yun Pyo Kang, Nathan P. Ward, Gina M. DeNicola
Published 2018-04-01

Long noncoding RNA DANCR promotes colorectal cancer proliferation and metastasis via miR-577 sponging

by Yong Wang, Zhi Lu, Ningnin Wang, Jianzhou Feng, Junjie Zhang, Lan Luan, Wei Zhao, Xiandong Zeng
Published 2018-05-01

Circular RNA circ-4099 is induced by TNF-α and regulates ECM synthesis by blocking miR-616-5p inhibition of Sox9 in intervertebral disc degeneration

by Hua Wang, Peiheng He, Hehai Pan, Jun long, Jianru Wang, Zemin Li, Hui Liu, Weiying Jiang, Zhaomin Zheng
Published 2018-04-01

Altered AKAP12 expression in portal fibroblasts and liver sinusoids mediates transition from hepatic fibrogenesis to fibrosis resolution

by Hye Shin Lee, Jinhyeok Choi, Taekwon Son, Hee-Jun Wee, Sung-Jin Bae, Ji Hae Seo, Ji Hyun Park, Soo Hyung Ryu, Danbi Lee, Myoung Kuk Jang, Eunsil Yu, Young-Hwa Chung, Kyu-Won Kim
Published 2018-04-01

Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification

by Jia Gu, Yan Lu, Menqing Deng, Ming Qiu, Yunfan Tian, Yue Ji, Pengyu Zong, Yongfeng Shao, Rui Zheng, Bin Zhou, Wei Sun, Xiangqing Kong
Published 2019-07-01

Genes that modulate the frequency of mutation at meiosis

by Ronald H. F. Hunter, Niels Einer-Jensen
Published 2018-04-01

The wide utility of rabbits as models of human diseases

by Pedro J. Esteves, Joana Abrantes, Hanna-Mari Baldauf, Lbachir BenMohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver T. Keppler, Katherine L. Knight, Xiang-Peng Kong, Dennis K. Lanning, Jacques Le Pendu, Ana Lemos de Matos, Jia Liu, Shuying Liu, Ana M. Lopes, Shan Lu, Sheila Lukehart, Yukari C. Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Jesús Tuñón, Wessel van der Loo, Michael Vaine, Laura E. Via, Shixia Wang, Rose Mage
Published 2018-05-01

Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

by Mi Nam Lee, Hee-Su Hwang, Sin-Hye Oh, Amir Roshanzadeh, Jung-Woo Kim, Ju Han Song, Eung-Sam Kim, Jeong-Tae Koh
Published 2018-11-01

Synapse development organized by neuronal activity-regulated immediate-early genes

by Seungjoon Kim, Hyeonho Kim, Ji Won Um
Published 2018-04-01

S-nitrosylation of transglutaminase 2 impairs fatty acid-stimulated contraction in hypertensive cardiomyocytes

by Eui Man Jeong, Chun Zi Jin, Ji Hyun Jang, Zai Hao Zhao, Chun Li Jin, Jin Hang Lee, Ki Baek Lee, Sung Joon Kim, In-Gyu Kim, Yin Hua Zhang
Published 2018-04-01

Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis

by Yong Zhang, Xiao-lan Wang, Min Zhou, Chao Kang, He-dong Lang, Meng-ting Chen, Suo-cheng Hui, Bin Wang, Man-tian Mi
Published 2018-04-01

Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration

by Jianle Wang, Majid Nisar, Chongan Huang, Xiangxiang Pan, Dongdong Lin, Gang Zheng, Haiming Jin, Deheng Chen, Naifeng Tian, Qianyu Huang, Yue Duan, Yingzhao Yan, Ke Wang, Congcong Wu, Jianing Hu, Xiaolei Zhang, Xiangyang Wang
Published 2018-11-01

Mechanisms and disease implications of sirtuin-mediated autophagic regulation

by In Hye Lee
Published 2019-09-01

Mitochondrial superoxide dismutase 2 mediates γ-irradiation-induced cancer cell invasion

by Chan-Hun Jung, Eun Mi Kim, Jie-Young Song, Jong Kuk Park, Hong-Duck Um
Published 2019-02-01

Special issue on hypoxia

by Eui-Ju Yeo
Published 2019-06-01

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

by Teppei Fujikawa, Yun-Hee Choi, Dong Joo Yang, Dong Min Shin, Jose Donato, Daisuke Kohno, Charlotte E. Lee, Carol F. Elias, Syann Lee, Ki Woo Kim
Published 2019-04-01

High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure

by Daniel Scheiber, Tomas Jelenik, Elric Zweck, Patrick Horn, Heinz-Peter Schultheiss, Dirk Lassner, Udo Boeken, Diyar Saeed, Malte Kelm, Michael Roden, Ralf Westenfeld, Julia Szendroedi
Published 2019-02-01