Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.

by Johan L M Björkegren, Sara Hägg, Husain A Talukdar, Hassan Foroughi Asl, Rajeev K Jain, Cecilia Cedergren, Ming-Mei Shang, Aránzazu Rossignoli, Rabbe Takolander, Olle Melander, Anders Hamsten, Tom Michoel, Josefin Skogsberg
Published 2014-02-01

Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease.

by Bruna Gigante, Rona J Strawbridge, Ilais Moreno Velasquez, Zahra Golabkesh, Angela Silveira, Anuj Goel, Damiano Baldassarre, Fabrizio Veglia, Elena Tremoli, Robert Clarke, Hugh Watkins, Anders Hamsten, Steve E Humphries, Ulf de Faire
Published 2015-01-01

Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

by Ci Song, Nancy L Pedersen, Chandra A Reynolds, Maria Sabater-Lleal, Stavroula Kanoni, Christina Willenborg, CARDIoGRAMplusC4D Consortium, Ann-Christine Syvänen, Hugh Watkins, Anders Hamsten, Jonathan A Prince, Erik Ingelsson
Published 2013-01-01

Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake.

by Sergej Popov, Hiroshi Takemori, Takeshi Tokudome, Yuanjie Mao, Kentaro Otani, Naoki Mochizuki, Nuno Pires, Maria João Pinho, Anders Franco-Cereceda, Lucia Torielli, Mara Ferrandi, Anders Hamsten, Patricio Soares-da-Silva, Per Eriksson, Alejandro M Bertorello, Laura Brion
Published 2014-01-01

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

by Daniel I Chasman, Guillaume Paré, Samia Mora, Jemma C Hopewell, Gina Peloso, Robert Clarke, L Adrienne Cupples, Anders Hamsten, Sekar Kathiresan, Anders Mälarstig, José M Ordovas, Samuli Ripatti, Alex N Parker, Joseph P Miletich, Paul M Ridker
Published 2009-11-01

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17.

by Martin Farrall, Fiona R Green, John F Peden, Per G Olsson, Robert Clarke, Mai-Lis Hellenius, Stephan Rust, Jacob Lagercrantz, Maria Grazia Franzosi, Helmut Schulte, Alisoun Carey, Gunnar Olsson, Gerd Assmann, Gianni Tognoni, Rory Collins, Anders Hamsten, Hugh Watkins
Published 2006-05-01

Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants

by Federica Laguzzi, Buamina Maitusong, Rona J. Strawbridge, Damiano Baldassarre, Fabrizio Veglia, Steve E. Humphries, Rainer Rauramaa, Sudhir Kurl, Andries J. Smit, Philippe Giral, Angela Silveira, Elena Tremoli, Anders Hamsten, Ulf de Faire, Bruna Gigante, Karin Leander, IMPROVE Study group
Published 2021-04-01

Data on the association between a simplified Mediterranean diet score and the incidence of combined, cardio and cerebro vascular events

by Fabrizio Veglia, Damiano Baldassarre, Ulf de Faire, Sudhir Kurl, Andries J. Smit, Rainer Rauramaa, Philippe Giral, Mauro Amato, Alessandro Di Minno, Alessio Ravani, Beatrice Frigerio, Samuela Castelnuovo, Daniela Sansaro, Daniela Coggi, Alice Bonomi, Calogero C. Tedesco, Elmo Mannarino, Steve E. Humphries, Anders Hamsten, Elena Tremoli
Published 2019-04-01

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.

by Cécilia G Maubaret, Klelia D Salpea, Casey E Romanoski, Lasse Folkersen, Jackie A Cooper, Coralea Stephanou, Ka Wah Li, Jutta Palmen, Anders Hamsten, Andrew Neil, Jeffrey W Stephens, Aldons J Lusis, Per Eriksson, Philippa J Talmud, Steve E Humphries, Simon Broome Research Group, EARSII consortium
Published 2013-01-01

Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease[S]

by Anna Aminoff, Helena Ledmyr, Petra Thulin, Kerstin Lundell, Leyla Nunez, Elisabeth Strandhagen, Charlotte Murphy, Ulf Lidberg, Jukka Westerbacka, Anders Franco-Cereceda, Jan Liska, Lars Bo Nielsen, Mats Gåfvels, Maria Nastase Mannila, Anders Hamsten, Hannele Yki-Järvinen, Dag Thelle, Per Eriksson, Jan Borén, Ewa Ehrenborg
Published 2010-01-01

Plasma lecithin:cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk

by Laura Calabresi, Damiano Baldassarre, Sara Simonelli, Monica Gomaraschi, Mauro Amato, Samuela Castelnuovo, Beatrice Frigerio, Alessio Ravani, Daniela Sansaro, Jussi Kauhanen, Rainer Rauramaa, Ulf de Faire, Anders Hamsten, Andries J. Smit, Elmo Mannarino, Steve E. Humphries, Philippe Giral, Fabrizio Veglia, Cesare R. Sirtori, Guido Franceschini, Elena Tremoli
Published 2011-08-01

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.

by Maria Sabater-Lleal, Anders Mälarstig, Lasse Folkersen, María Soler Artigas, Damiano Baldassarre, Maryam Kavousi, Peter Almgren, Fabrizio Veglia, Guy Brusselle, Albert Hofman, Gunnar Engström, Oscar H Franco, Olle Melander, Gabrielle Paulsson-Berne, Hugh Watkins, Per Eriksson, Steve E Humphries, Elena Tremoli, Ulf de Faire, Martin D Tobin, Anders Hamsten
Published 2014-01-01

Involvement of SIK3 in glucose and lipid homeostasis in mice.

by Tatsuya Uebi, Yumi Itoh, Osamu Hatano, Ayako Kumagai, Masato Sanosaka, Tsutomu Sasaki, Satoru Sasagawa, Junko Doi, Keita Tatsumi, Kuniko Mitamura, Eiichi Morii, Katsuyuki Aozasa, Tomohiro Kawamura, Meinoshin Okumura, Jun Nakae, Hajime Takikawa, Toshio Fukusato, Minako Koura, Mayumi Nish, Anders Hamsten, Angela Silveira, Alejandro M Bertorello, Kazuo Kitagawa, Yasuo Nagaoka, Hidehisa Kawahara, Takeshi Tomonaga, Tetsuji Naka, Shigeo Ikegawa, Noriyuki Tsumaki, Junichiro Matsuda, Hiroshi Takemori
Published 2012-01-01

Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Athero...

by Sara Hägg, Josefin Skogsberg, Jesper Lundström, Peri Noori, Roland Nilsson, Hua Zhong, Shohreh Maleki, Ming-Mei Shang, Björn Brinne, Maria Bradshaw, Vladimir B Bajic, Ann Samnegård, Angela Silveira, Lee M Kaplan, Bruna Gigante, Karin Leander, Ulf de Faire, Stefan Rosfors, Ulf Lockowandt, Jan Liska, Peter Konrad, Rabbe Takolander, Anders Franco-Cereceda, Eric E Schadt, Torbjörn Ivert, Anders Hamsten, Jesper Tegnér, Johan Björkegren
Published 2009-12-01

The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals

by Rona J. Strawbridge, Keira J. A. Johnston, Mark E. S. Bailey, Damiano Baldassarre, Breda Cullen, Per Eriksson, Ulf deFaire, Amy Ferguson, Bruna Gigante, Philippe Giral, Nicholas Graham, Anders Hamsten, Steve E. Humphries, Sudhir Kurl, Donald M. Lyall, Laura M. Lyall, Jill P. Pell, Matteo Pirro, Kai Savonen, Andries J. Smit, Elena Tremoli, Tomi-Pekka Tomainen, Fabrizio Veglia, Joey Ward, Bengt Sennblad, Daniel J. Smith
Published 2021-01-01

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.

by Lasse Folkersen, Eric Fauman, Maria Sabater-Lleal, Rona J Strawbridge, Mattias Frånberg, Bengt Sennblad, Damiano Baldassarre, Fabrizio Veglia, Steve E Humphries, Rainer Rauramaa, Ulf de Faire, Andries J Smit, Philippe Giral, Sudhir Kurl, Elmo Mannarino, Stefan Enroth, Åsa Johansson, Sofia Bosdotter Enroth, Stefan Gustafsson, Lars Lind, Cecilia Lindgren, Andrew P Morris, Vilmantas Giedraitis, Angela Silveira, Anders Franco-Cereceda, Elena Tremoli, IMPROVE study group, Ulf Gyllensten, Erik Ingelsson, Søren Brunak, Per Eriksson, Daniel Ziemek, Anders Hamsten, Anders Mälarstig
Published 2017-04-01

Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response

by Samuel Röhl, MD, PhD, Urszula Rykaczewska, MSc, Till Seime, MSc, Bianca E. Suur, MSc, Maria Gonzalez Diez, PhD, Jesper R. Gådin, PhD, Anastasiia Gainullina, MSc, Alexey A. Sergushichev, PhD, Robert Wirka, MD, PhD, Mariette Lengquist, MSc, Malin Kronqvist, MSc, Otto Bergman, PhD, Jacob Odeberg, MD, PhD, Jan H.N. Lindeman, MD, PhD, Thomas Quertermous, MD, PhD, Anders Hamsten, MD, PhD, Per Eriksson, MSc, PhD, Ulf Hedin, MD, PhD, Anton Razuvaev, MD, PhD, Ljubica Perisic Matic, MSc, PhD
Published 2020-01-01

Genome-wide analysis yields new loci associating with aortic valve stenosis

by Anna Helgadottir, Gudmar Thorleifsson, Solveig Gretarsdottir, Olafur A. Stefansson, Vinicius Tragante, Rosa B. Thorolfsdottir, Ingileif Jonsdottir, Thorsteinn Bjornsson, Valgerdur Steinthorsdottir, Niek Verweij, Jonas B. Nielsen, Wei Zhou, Lasse Folkersen, Andreas Martinsson, Mahyar Heydarpour, Siddharth Prakash, Gylfi Oskarsson, Tomas Gudbjartsson, Arnar Geirsson, Isleifur Olafsson, Emil L. Sigurdsson, Peter Almgren, Olle Melander, Anders Franco-Cereceda, Anders Hamsten, Lars Fritsche, Maoxuan Lin, Bo Yang, Whitney Hornsby, Dongchuan Guo, Chad M. Brummett, Gonçalo Abecasis, Michael Mathis, Dianna Milewicz, Simon C. Body, Per Eriksson, Cristen J. Willer, Kristian Hveem, Christopher Newton-Cheh, J. Gustav Smith, Ragnar Danielsen, Gudmundur Thorgeirsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Hilma Holm, Kari Stefansson
Published 2018-03-01

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.

by Shafqat Ahmad, Gull Rukh, Tibor V Varga, Ashfaq Ali, Azra Kurbasic, Dmitry Shungin, Ulrika Ericson, Robert W Koivula, Audrey Y Chu, Lynda M Rose, Andrea Ganna, Qibin Qi, Alena Stančáková, Camilla H Sandholt, Cathy E Elks, Gary Curhan, Majken K Jensen, Rulla M Tamimi, Kristine H Allin, Torben Jørgensen, Soren Brage, Claudia Langenberg, Mette Aadahl, Niels Grarup, Allan Linneberg, Guillaume Paré, InterAct Consortium, DIRECT Consortium, Patrik K E Magnusson, Nancy L Pedersen, Michael Boehnke, Anders Hamsten, Karen L Mohlke, Louis T Pasquale, Oluf Pedersen, Robert A Scott, Paul M Ridker, Erik Ingelsson, Markku Laakso, Torben Hansen, Lu Qi, Nicholas J Wareham, Daniel I Chasman, Göran Hallmans, Frank B Hu, Frida Renström, Marju Orho-Melander, Paul W Franks
Published 2013-01-01

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.

by Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, Anubha Mahajan, Letizia Marullo, Gudmar Thorleifsson, Sara Hӓgg, Jouke-Jan Hottenga, Claes Ladenvall, Janina S Ried, Thomas W Winkler, Sara M Willems, Natalia Pervjakova, Tõnu Esko, Marian Beekman, Christopher P Nelson, Christina Willenborg, Steven Wiltshire, Teresa Ferreira, Juan Fernandez, Kyle J Gaulton, Valgerdur Steinthorsdottir, Anders Hamsten, Patrik K E Magnusson, Gonneke Willemsen, Yuri Milaneschi, Neil R Robertson, Christopher J Groves, Amanda J Bennett, Terho Lehtimӓki, Jorma S Viikari, Johan Rung, Valeriya Lyssenko, Markus Perola, Iris M Heid, Christian Herder, Harald Grallert, Martina Müller-Nurasyid, Michael Roden, Elina Hypponen, Aaron Isaacs, Elisabeth M van Leeuwen, Lennart C Karssen, Evelin Mihailov, Jeanine J Houwing-Duistermaat, Anton J M de Craen, Joris Deelen, Aki S Havulinna, Matthew Blades, Christian Hengstenberg, Jeanette Erdmann, Heribert Schunkert, Jaakko Kaprio, Martin D Tobin, Nilesh J Samani, Lars Lind, Veikko Salomaa, Cecilia M Lindgren, P Eline Slagboom, Andres Metspalu, Cornelia M van Duijn, Johan G Eriksson, Annette Peters, Christian Gieger, Antti Jula, Leif Groop, Olli T Raitakari, Chris Power, Brenda W J H Penninx, Eco de Geus, Johannes H Smit, Dorret I Boomsma, Nancy L Pedersen, Erik Ingelsson, Unnur Thorsteinsdottir, Kari Stefansson, Samuli Ripatti, Inga Prokopenko, Mark I McCarthy, Andrew P Morris, ENGAGE Consortium
Published 2015-07-01