A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

by Mann, Aman P., Scodeller, Pablo, Hussain, Sazid, Joo, Jinmyoung, Braun, Gary B., Mölder, Tarmo, She, Zhi-Gang, Kotamraju, Venkata Ramana, Ranscht, Barbara, Krajewski, Stan, Teesalu, Tambet, Sailor, Michael J., Ruoslahti, Erkki, Bhatia, Sangeeta N, Kwon, Ester
Published 2017

In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites

by Gural, Nil, Mancio Silva, Liliana, Miller, Alex B, Galstian, Ani, Butty, Vincent L, Levine, Stuart S, Patrapuvich, Rapatbhorn, Desai, Salil P, Mikolajczak, Sebastian A, Kappe, Stefan H. I., Fleming, Heather, March-Riera, Sandra, Sattabongkot, Jetsumon, Bhatia, Sangeeta N
Published 2019

A single-cell liver atlas of Plasmodium vivax infection

by Mancio-Silva, Liliana, Gural, Nil, Real, Eliana, Wadsworth, Marc H, Butty, Vincent L, March, Sandra, Nerurkar, Niketa, Hughes, Travis K, Roobsoong, Wanlapa, Fleming, Heather E, Whittaker, Charlie A, Levine, Stuart S, Sattabongkot, Jetsumon, Shalek, Alex K, Bhatia, Sangeeta N
Published 2022

Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy

by El-Haibi, Christelle P., Bell, George W., Zhang, Jiangwen, Collmann, Anthony Y., Scherber, Cally M., Csizmadia, Eva, Mariani, Odette, Zhu, Cuihua, Campagne, Antoine, Toner, Mehmet, Irimia, Daniel, Vincent-Salomon, Anne, Karnoub, Antoine E., Wood, David K., Bhatia, Sangeeta N
Published 2013

Cancer Vulnerabilities Unveiled by Genomic Loss

by Nijhawan, Deepak, Zack, Travis I, Ren, Yin, Strickland, Matthew R, Lamothe, Rebecca, Schumacher, Steven E, Tsherniak, Aviad, Besche, Henrike C, Rosenbluh, Joseph, Shehata, Shyemaa, Cowley, Glenn S., Weir, Barbara A, Goldberg, Alfred L, Mesirov, Jill P., Root, David E, Beroukhim, Rameen, Hahn, William C., Bhatia, Sangeeta N
Published 2014

Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Target ID4

by Ren, Yin, von Maltzhan, Geoffrey, Agrawal, Amit, Mesirov, Jill P., Lo, Justin H., Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Tamayo, Pablo, Karst, Alison M., Liu, Joyce F., Hirsch, Michelle S., Drapkin, Ronny, Root, David E., Fogal, Valentina, Ruoslahti, Erkki, Hahn, William C., Bhatia, Sangeeta N
Published 2014

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease

by Stevens, Kelly R., Scull, Margaret A., Ramanan, Vyas, Fortin, Chelsea L., Chaturvedi, Ritika R., Knouse, Kristin Ann, Xiao, Jing W., Fung, Canny, Mirabella, Teodelinda, Chen, Amanda X., McCue, Margaret Grace, Yang, Michael T., Fleming, Heather, Chung, Kwanghun, de Jong, Ype P., Chen, Christopher S., Rice, Charles M., Bhatia, Sangeeta N
Published 2021

In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease

by Stevens, Kelly R., Scull, Margaret A., Ramanan, Vyas, Fortin, Chelsea L., Chaturvedi, Ritika R., Knouse, Kristin Ann, Xiao, Jing W., Fung, Canny, Mirabella, Teodelinda, Chen, Amanda X., McCue, Margaret Grace, Yang, Michael T., Fleming, Heather, Chung, Kwanghun, de Jong, Ype P., Chen, Christopher S., Rice, Charles M., Bhatia, Sangeeta N
Published 2022

Distinct Hepatic Gene‐Expression Patterns of NAFLD in Patients With Obesity

by Subudhi, Sonu, Drescher, Hannah K, Dichtel, Laura E, Bartsch, Lea M, Chung, Raymond T, Hutter, Matthew M, Gee, Denise W, Meireles, Ozanan R, Witkowski, Elan R, Gelrud, Louis, Masia, Ricard, Osganian, Stephanie A, Gustafson, Jenna L, Rwema, Steve, Bredella, Miriam A, Bhatia, Sangeeta N, Warren, Andrew, Miller, Karen K, Lauer, Georg M, Corey, Kathleen E
Published 2022

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

by Viswanathan, Srinivas R., Nogueira, Marina F., Buss, Colin G., Krill-Burger, John M., Wawer, Mathias J., Malolepsza, Edyta, Berger, Ashton C., Choi, Peter S., Shih, Juliann, Taylor, Alison M., Tanenbaum, Benjamin, Pedamallu, Chandra Sekhar, Cherniack, Andrew D., Tamayo, Pablo, Strathdee, Craig A., Lage, Kasper, Carr, Steven A., Schenone, Monica, Bhatia, Sangeeta N, Vazquez, Francisca, Tsherniak, Aviad, Hahn, William C., Meyerson, Matthew
Published 2020

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

by Ren, Yin, Meyerson, Matthew L., Drapkin, Ronny, Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Rusin, Scott, Scott, Justine A., East, Alexandra, Ali, Levi D., Lizotte, Patrick H., Wong, Terence C., Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H., Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Mesirov, Jill P., Garraway, Levi A., Lander, Eric S., Root, David E., Hahn, William C., Bhatia, Sangeeta N
Published 2012

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

by Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March-Riera, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Published 2020

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

by Geller, Leore T., Barzily-Rokni, Michal, Danino, Tal, Jonas, Oliver H., Shental, Noam, Nejman, Deborah, Gavert, Nancy, Zwang, Yaara, Cooper, Zachary A., Shee, Kevin, Thaiss, Christoph A., Reuben, Alexandre, Livny, Jonathan, Avraham, Roi, Frederick, Dennie T., Ligorio, Matteo, Chatman, Kelly, Johnston, Stephen E., Mosher, Carrie M., Brandis, Alexander, Fuks, Garold, Gurbatri, Candice, Gopalakrishnan, Vancheswaran, Kim, Michael, Hurd, Mark W., Katz, Matthew, Fleming, Jason, Maitra, Anirban, Smith, David A., Skalak, Matthew T., Bu, Jeffrey, Michaud, Monia, Trauger, Sunia A., Barshack, Iris, Golan, Talia, Sandbank, Judith, Flaherty, Keith T., Mandinova, Anna, Garrett, Wendy S., Thayer, Sarah P., Ferrone, Cristina R., Huttenhower, Curtis, Bhatia, Sangeeta N., Gevers, Dirk, Wargo, Jennifer A., Golub, Todd R., Straussman, Ravid
Published 2020

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

by Phillips, M. A., Lotharius, J., Marsh, K., White, J., Dayan, A., White, K. L., Njoroge, J. W., El Mazouni, F., Lao, Y., Kokkonda, S., Tomchick, D. R., Deng, X., Laird, T., Ng, C. L., Fidock, D. A., Wittlin, S., Lafuente-Monasterio, M., Benito, F. J. G., Alonso, L. M. S., Martinez, M. S., Jimenez-Diaz, M. B., Bazaga, S. F., Angulo-Barturen, I., Haselden, J. N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A.-M, Kocken, C., Sauerwein, R., Dechering, K., Avery, V. M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K. S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., Rogers, M. J., Rathod, P. K., Burrows, J. N., Charman, S. A., Bhatia, Sangeeta N, March-Riera, Sandra
Published 2017

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

by Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Yesmalie, Alemán Resto, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Cassera, Maria Belen, Ken, Chih-Chien Cheng, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D'Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Sa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A., Bhatia, Sangeeta N
Published 2017

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax

by March-Riera, Sandra, Ng, Shengyong, Velmurugan, Soundarapandian, Galstian, Ani, Shan, Jing, Logan, David J., Carpenter, Anne E., Thomas, David, Sim, B. Kim Lee, Mota, Maria M., Hoffman, Stephen L.
Published 2014