Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

by Burkard, Mark E., Maciejowski, John, Rodriguez-Bravo, Veronica, Repka, Michael, Lowery, Drew M., Clauser, Karl R., Shokat, Kevan M., Jallepalli, Prasad V., Zhang, Chao, Ph. D. Massachusetts Institute of Technology, Carr, Steven A, Yaffe, Michael B
Published 2010

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

by Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K, Regev, Aviv
Published 2016

Hippocampal subfield volumetry from structural isotropic 1 mm3 MRI scans: A note of caution

by Bakker, A., Berron, D., Carr, V.A, Chételat, G., Daugherty, A.M, de Flores, R., la Joie, R., Mueller, S.G, Olsen, R.K, Raz, N., Stark, C.E.L, Wang, L., Wisse, L.E.M, Yushkevich, P.A
Published 2021

An e-science environment for service crystallography: from submission to dissemination

by Coles, Simon J., Frey, Jeremy G., Hursthouse, Michael B., Light, Mark E., Milsted, Andrew J., Carr, Leslie A., De Roure, David, Gutteridge, Christopher J., Mills, Hugo R., Meacham, Ken E., Surridge, Michael, Lyon, Elizabeth, Heery, Rachel, Duke, Monica, Day, Michael
Published 2006

Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway

by Zhu, J. Julius, Clauser, Karl R., Guan, Ji-Song, Gao, Jun, Xie, Zhigang, Zhou, Ying, Durak, Omer, Tsai, Li-Huei, Zhang, Lei, Ph. D Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, fl. 2014, Carr, Steven A, Su, S., Joseph, Nadine F.
Published 2012

Dynamic profiling of the protein life cycle in response to pathogens

by Jovanovic, M., Mertins, P., Przybylski, D., Chevrier, N., Satija, R., Rodriguez, E. H., Fields, A. P., Schwartz, S., Raychowdhury, R., Mumbach, M. R., Eisenhaure, T., Rabani, M., Gennert, D., Lu, D., Delorey, T., Weissman, J. S., Carr, S. A., Hacohen, N., Regev, Aviv, Rooney, Michael Steven
Published 2016

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

by Villar, Rina F., Weaver, Grant C., Kanekiyo, Masaru, Wheatley, Adam K., Yassine, Hadi M., Costello, Catherine E., Chandler, Kevin B., McTamney, Patrick. M., Nabel, Gary J., McDermott, Adrian B., Mascola, John R., Lingwood, Daniel, Patel, Jinal, Carr, Steven A
Published 2017

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

by Parnas, Oren, Jovanovic, Marko, Eisenhaure, Thomas M, Herbst, Rebecca H, Ye, Chun Jimmie, Przybylski, Dariusz, Tirosh, Itay, Satija, Rahul, Raychowdhury, Raktima, Mertins, Philipp, Carr, Steven A, Hacohen, Nir, Regev, Aviv, Dixit, Atray C., Platt, Randall Jeffrey, Sanjana, Neville E, Shalem, Ophir, Zhang, Feng
Published 2017

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

by Yaffe, Michael B., Brummelkamp, Thijn R., Reinhardt, Hans, Ostheimer, Gerard, Gardino, Alexandra Kate, van Vugt, Marcel A. T. M., Smerdon, Stephen J., Carr, Steven A., Lewis, Timothy A., Pawson, Tony, Li, Jeijin, Keezer, Susan M., Miao, Hua, Tan, Chris S., Ong, Shao-En, Linding, Rune
Published 2010

The SARS-CoV-2 RNA-protein interactome in infected human cells

by Schmidt, Nora, Lareau, Caleb A., Keshishian, Hasmik, Ganskih, Sabina, Schneider, Cornelius, Hennig, Thomas, Melanson, Randy, Werner, Simone, Wei, Yuanjie, Zimmer, Matthias, Ade, Jens, Kirschner, Luisa, Zielinski, Sebastian, Dölken, Lars, Lander, Eric Steven, Caliskan, Neva, Fischer, Utz, Vogel, Jörg, Carr, Steven A., Bodem, Jochen, Munschauer, Mathias
Published 2021

Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

by Andreev, O.A, Carr, C.A, Chung, Y.J, Crump, N.T, Curtis, M.K, Fournier, M., Gunadasa-Rohling, M., Hulikova, A., Loonat, A.A, Milne, T.A, Moshnikova, A., Park, K.C, Reshetnyak, Y.K, Riley, P.R, Smart, N., Swietach, P., Trafford, A.W, Wilson, A.
Published 2022

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation

by Graham, Daniel B., Lefkovith, Ariel, Deelen, Patrick, de Klein, Niek, Boroughs, Angela, Desch, A. Nicole, Ng, Aylwin C.Y, Petersen, Christine P., Bhan, Atul K., Wijmenga, Cisca, Varma, Mukund Madhav, Guzman, Gaelen Donnelly, Schenone, Monica, Rivas, Manuel A, Carr, Steven A, Xavier, Ramnik Joseph, Daly, Mark J.
Published 2017

Identifying the proteins to which small-molecule probes and drugs bind in cells

by Ong, Shao-En, Schenone, Monica, Margolin, Adam A., Li, Xiaoyu, Do, Kathy, Doud, Mary Kathryn, Mani, D. R., Kuai, Letian, Wang, Xiang, Wood, John L., Tolliday, Nicola J., Koehler, Angela Nicole, Marcaurelle, Lisa A., Golub, Todd R., Gould, Robert J., Schreiber, Stuart L., Carr, Steven A.
Published 2009

Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation

by Tucker, Elena J, Hershman, Steven G, Belcher-Timme, Casey A, Patel, Jinal, Goldberger, Olga A., Christodoulou, John, Silberstein, Jonathon M, McKenzie, Matthew, Ryan, Michael T, Compton, Alison G, Jaffe, Jacob D., Carr, Steven A., Calvo, Sarah E., RajBhandary, Uttam L, Thorburn, David R, Mootha, Vamsi K., Koehrer, Caroline
Published 2014

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5' Sites

by Schwartz, Schraga, Mumbach, Maxwell R, Jovanovic, Marko, Wang, Tim, Maciag, Karolina, Bushkin, G. Guy, Mertins, Philipp, Ter-Ovanesyan, Dmitry, Habib, Naomi, Cacchiarelli, Davide, Sanjana, Neville E, Freinkman, Elizaveta, Pacold, Michael E., Satija, Rahul, Hacohen, Nir, Zhang, Feng, Regev, Aviv, Mikkelsen, Tarjei Sigurd 1978-, Carr, Steven A, Lander, Eric Steven
Published 2015

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation

by Basak, Anindita, Munschauer, Mathias, Lareau, Caleb A., Montbleau, Kara E., Ulirsch, Jacob C., Hartigan, Christina R., Schenone, Monica, Lian, John, Wang, Yaomei, Huang, Yumin, Wu, Xianfang, Gehrke, Lee, Rice, Charles M., An, Xiuli, Christou, Helen A., Mohandas, Narla, Carr, Steven A., Chen, Jane-Jane, Orkin, Stuart H., Lander, Eric Steven, Sankaran, Vijay G.
Published 2021

Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features

by Madison, Jon M, Duong, Karen, Vieux, Ellen F, Udeshi, Namrata D, Iqbal, Sumaiya, Requadt, Elise, Fereshetian, Shaunt, Lewis, Michael C, Gomes, Antonio S, Pierce, Kerry A, Platt, Randall J, Zhang, Feng, Campbell, Arthur J, Lal, Dennis, Wagner, Florence F, Clish, Clary B, Carr, Steven A, Sheng, Morgan, Scolnick, Edward M, Cottrell, Jeffrey R
Published 2021

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

by Szucs, Matthew J, Ammendolia, Dustin A, MacMullan, Melanie A, Rakoff-Nahoum, Seth, Mead, Benjamin Elliott, Ordovas-Montanes, Jose Manuel, Braun, Alexandra Provost, Levy, Lauren, Saluja, Prerna Bhargava, Yin, Xiaolei, Hughes, Travis K., Wadsworth, Marc Havens, Ahmad, Rushdy, Carr, Steven A, Langer, Robert S, Collins, James J., Shalek, Alexander K, Karp, Jeffrey Michael
Published 2018

Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits

by Chevrier, Nicolas, Mertins, Philipp, Artyomov, Maxim N., Shalek, Alex K., Iannacone, Matteo, Ciaccio, Mark F, Gat-Viks, Irit, Tonti, Elena, DeGrace, Marciela M., Clauser, Karl R., Garber, Manuel, Eisenhaure, Thomas, Yosef, Nir, Robinson, Jacob, Sutton, Amy, Andersen, Mette S., Root, David E, von Andrian, Ulrich, Jones, Richard Bradley, Park, Hongkun, Carr, Steven A., Regev, Aviv, Amit, Ido, Hacohen, Nir
Published 2014

ZBED6, a Novel Transcription Factor Derived from a Domesticated DNA Transposon Regulates IGF2 Expression and Muscle Growth

by Andersson, Leif, Hjalm, Goran, Andersson, Goran, Lindblad-Toh, Kerstin, Wadelius, Claes, Kullander, Klas, Zierath, Juleen R., Ponten, Fredrik, De, Sachinandan, Stromberg, Sara, Yan, Jie, Barres, Romain, Lindroth, Anders M., Gnirke, Andreas, Saenz-Vash, Veronica, Wang, Li, Zhang, Xiaolan, Larhammar, Martin, Wallerman, Ola, Jaffe, Jacob D., Jiang, Lin, Markljung, Ellen, Mikkelsen, Tarjei Sigurd 1978-, Carr, Steven A, Lander, Eric Steven
Published 2010