Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

by Schepers, Arnout G, Shan, Jing, Cox, Andrew G, Huang, Ada, Evans, Helen, Walesky, Chad, Fleming, Heather E, Goessling, Wolfram, Bhatia, Sangeeta N
Published 2022

Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

by Schepers, Arnout G, Shan, Jing, Cox, Andrew G, Huang, Ada, Evans, Helen, Walesky, Chad, Fleming, Heather E, Goessling, Wolfram, Bhatia, Sangeeta N
Published 2022

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

by North, Trista E., Vedder, Lea M., Lord, Allegra M., Wishnok, John S., Tannenbaum, Steven Robert, Zon, Leonard I., Goessling, Wolfram, Badu, I. Ramesh
Published 2011

Identification of small molecules for human hepatocyte expansion and iPS differentiation

by Shan, Jing, Ross, Nathan T., Logan, David J., Thomas, David, Duncan, Stephen A., North, Trista E., Goessling, Wolfram, Carpenter, Anne E., Schwartz, Robert E., Bhatia, Sangeeta N
Published 2014

Functional compensation precedes recovery of tissue mass following acute liver injury

by Walesky, Chad M, Kolb, Kellie E, Winston, Carolyn L, Henderson, Jake, Kruft, Benjamin, Fleming, Ira, Ko, Sungjin, Monga, Satdarshan P, Mueller, Florian, Apte, Udayan, Shalek, Alex K, Goessling, Wolfram
Published 2022

Estrogen Acts Through Estrogen Receptor 2b to Regulate Hepatobiliary Fate During Vertebrate Development

by Chaturantabut, Saireudee, Shwartz, Arkadi, Garnaas, Maija K., LaBella, Kyle, Li, Chia‐Cheng, Carroll, Kelli J., Cutting, Claire C., Budrow, Nadine, Palaria, Amrita, Gorelick, Daniel A., Tremblay, Kimberly D., North, Trista E., Goessling, Wolfram
Published 2022

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

by Bao, Xiaoyan Robert, Ong, Shao-En, Goldberger, Olga, Peng, Jun, Sharma, Rohit, Thompson, Dawn A, Vafai, Scott B, Cox, Andrew G, Marutani, Eizo, Ichinose, Fumito, Goessling, Wolfram, Carr, Steven A, Clish, Clary B, Mootha, Vamsi K, Regev, Aviv
Published 2016

Mutation mapping and identification by whole-genome sequencing

by Leshchiner, Ignaty, Alexa, Kristen, Kelsey, Peter, Adzhubey, Ivan, Austin-Tse, Christina A., Cooney, Jeffrey D., Anderson, Heidi, King, Matthew J., Stottmann, Rolf W., Garnaas, Maija K., Ha, Seungshin, Drummond, Iain A., Paw, Barry H., North, Trista E., Beier, David R., Goessling, Wolfram, Sunyaev, Shamil R.
Published 2012

Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human ...

by Chaturantabut, Saireudee, Shwartz, Arkadi, Evason, Kimberley J., Cox, Andrew G., Labella, Kyle, Schepers, Arnout, Yang, Song, Acuña, Mariana, Houvras, Yariv, Mancio Silva, Liliana, Romano, Shannon, Gorelick, Daniel A., Cohen, David E., Zon, Leonard I., Bhatia, Sangeeta N., North, Trista E., Goessling, Wolfram, Bhatia, Sangeeta N
Published 2020

Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

by Cox, Andrew G., Tsomides, Allison, Kim, Andrew J., Saunders, Diane, Hwang, Katie L., Evason, Kimberley J., Heidel, Jerry, Brown, Kristin K., Yuan, Min, Lien, Evan C., Lee, Byung Cheon, Nissim, Sahar, Dickinson, Bryan, Chhangawala, Sagar, Asara, John M., Houvras, Yariv, Gladyshev, Vadim N., Goessling, Wolfram, Chang, Christopher J. 1974-
Published 2017

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

by Cox, Andrew G, Tsomides, Allison, Yimlamai, Dean, Hwang, Katie L, Miesfeld, Joel, Galli, Giorgio G, Fowl, Brendan H, Fort, Michael, Ma, Kimberly Y, Sullivan, Mark R, Hosios, Aaron M, Snay, Erin, Yuan, Min, Brown, Kristin K, Lien, Evan C, Chhangawala, Sagar, Steinhauser, Matthew L, Asara, John M, Houvras, Yariv, Link, Brian, Vander Heiden, Matthew G, Camargo, Fernando D, Goessling, Wolfram
Published 2020