HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity.

by Nobuyuki Matoba, Adam S Husk, Brian W Barnett, Michelle M Pickel, Charles J Arntzen, David C Montefiori, Atsushi Takahashi, Kazunobu Tanno, Satoshi Omura, Huyen Cao, Jason P Mooney, Carl V Hanson, Haruo Tanaka
Published 2010-06-01

Inhibition of adaptive immune responses leads to a fatal clinical outcome in SIV-infected pigtailed macaques but not vervet African green monkeys.

by Jörn E Schmitz, Roland C Zahn, Charles R Brown, Melisa D Rett, Ming Li, Haili Tang, Sarah Pryputniewicz, Russell A Byrum, Amitinder Kaur, David C Montefiori, Jonathan S Allan, Simoy Goldstein, Vanessa M Hirsch
Published 2009-12-01

Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein.

by Russell Vassell, Yong He, Prasad Vennakalanti, Antu K Dey, Min Zhuang, Wei Wang, Yide Sun, Zohar Biron-Sorek, Indresh K Srivastava, Celia C LaBranche, David C Montefiori, Susan W Barnett, Carol D Weiss
Published 2015-01-01

Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system.

by Robert J McLinden, Celia C Labranche, Agnès-Laurence Chenine, Victoria R Polonis, Michael A Eller, Lindsay Wieczorek, Christina Ochsenbauer, John C Kappes, Stephen Perfetto, David C Montefiori, Nelson L Michael, Jerome H Kim
Published 2013-01-01

HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge

by Andrew T. Jones, Xiaoying Shen, Korey L. Walter, Celia C. LaBranche, Linda S. Wyatt, Georgia D. Tomaras, David C. Montefiori, Bernard Moss, Dan H. Barouch, John D. Clements, Pamela A. Kozlowski, Raghavan Varadarajan, Rama Rao Amara
Published 2019-02-01

9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity.

by James J Kobie, Danielle C Alcena, Bo Zheng, Peter Bryk, Jonelle L Mattiacio, Matthew Brewer, Celia Labranche, Faith M Young, Stephen Dewhurst, David C Montefiori, Alexander F Rosenberg, Changyong Feng, Xia Jin, Michael C Keefer, Ignacio Sanz
Published 2012-01-01

Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.

by S Gnanakaran, Marcus G Daniels, Tanmoy Bhattacharya, Alan S Lapedes, Anurag Sethi, Ming Li, Haili Tang, Kelli Greene, Hongmei Gao, Barton F Haynes, Myron S Cohen, George M Shaw, Michael S Seaman, Amit Kumar, Feng Gao, David C Montefiori, Bette Korber
Published 2010-01-01

Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections.

by Kshitij Wagh, Michael S Seaman, Marshall Zingg, Tomas Fitzsimons, Dan H Barouch, Dennis R Burton, Mark Connors, David D Ho, John R Mascola, Michel C Nussenzweig, Jeffrey Ravetch, Rajeev Gautam, Malcolm A Martin, David C Montefiori, Bette Korber
Published 2018-03-01

Isolation of monoclonal antibodies with predetermined conformational epitope specificity.

by Anton M Sholukh, Muhammad M Mukhtar, Michael Humbert, Sosthène S Essono, Jennifer D Watkins, Hemant K Vyas, Vivekanandan Shanmuganathan, Girish Hemashettar, Maria Kahn, Shiu-Lok Hu, David C Montefiori, Victoria R Polonis, Peter H Schur, Ruth M Ruprecht
Published 2012-01-01

Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants.

by Rachel P J Lai, Michael S Seaman, Paul Tonks, Frank Wegmann, David J Seilly, Simon D W Frost, Celia C LaBranche, David C Montefiori, Antu K Dey, Indresh K Srivastava, Quentin Sattentau, Susan W Barnett, Jonathan L Heeney
Published 2012-01-01

Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.

by Samir K Lakhashe, Wendy Wang, Nagadenahalli B Siddappa, Girish Hemashettar, Patricia Polacino, Shiu-Lok Hu, François Villinger, James G Else, Francis J Novembre, John K Yoon, Sandra J Lee, David C Montefiori, Ruth M Ruprecht, Robert A Rasmussen
Published 2011-01-01

Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.

by Amit Kumar, Claire E P Smith, Elena E Giorgi, Joshua Eudailey, David R Martinez, Karina Yusim, Ayooluwa O Douglas, Lisa Stamper, Erin McGuire, Celia C LaBranche, David C Montefiori, Genevieve G Fouda, Feng Gao, Sallie R Permar
Published 2018-04-01

Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans.

by Nelson R Wu, Nathan I Nicely, Esther M Lee, Rachel K Reed, Brian E Watts, Fangping Cai, William E Walkowicz, Baptiste Aussedat, Julia A Jones, Amanda Eaton, Ashley M Trama, S Munir Alam, David C Montefiori, Barton F Haynes, Kevin O Saunders
Published 2019-12-01

Induction of Tier 1 HIV Neutralizing Antibodies by Envelope Trimers Incorporated into a Replication Competent Vesicular Stomatitis Virus Vector

by C. Anika Bresk, Tamara Hofer, Sarah Wilmschen, Marina Krismer, Anja Beierfuß, Grégory Effantin, Winfried Weissenhorn, Michael J. Hogan, Andrea P. O. Jordan, Rebecca S. Gelman, David C. Montefiori, Hua-Xin Liao, Joern E. Schmitz, Barton F. Haynes, Dorothee von Laer, Janine Kimpel
Published 2019-02-01

Safety and immunogenicity of an HIV adenoviral vector boost after DNA plasmid vaccine prime by route of administration: a randomized clinical trial.

by Beryl A Koblin, Martin Casapia, Cecilia Morgan, Li Qin, Zhixue Maggie Wang, Olivier D Defawe, Lindsey Baden, Paul Goepfert, Georgia D Tomaras, David C Montefiori, M Juliana McElrath, Lilian Saavedra, Chuen-Yen Lau, Barney S Graham, NIAID HIV Vaccine Trials Network
Published 2011-01-01

R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.

by Nagadenahalli B Siddappa, Jennifer D Watkins, Klemens J Wassermann, Ruijiang Song, Wendy Wang, Victor G Kramer, Samir Lakhashe, Michael Santosuosso, Mark C Poznansky, Francis J Novembre, François Villinger, James G Else, David C Montefiori, Robert A Rasmussen, Ruth M Ruprecht
Published 2010-07-01

A single gp120 residue can affect HIV-1 tropism in macaques.

by Gregory Q Del Prete, Brandon F Keele, Jeannine Fode, Keyur Thummar, Adrienne E Swanstrom, Anthony Rodriguez, Alice Raymond, Jacob D Estes, Celia C LaBranche, David C Montefiori, Vineet N KewalRamani, Jeffrey D Lifson, Paul D Bieniasz, Theodora Hatziioannou
Published 2017-09-01

Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells.

by Juan Pablo Jaworski, Shelly J Krebs, Maria Trovato, Dina N Kovarik, Zachary Brower, William F Sutton, Garrett Waagmeester, Rossella Sartorius, Luciana D'Apice, Antonella Caivano, Nicole A Doria-Rose, Delphine Malherbe, David C Montefiori, Susan Barnett, Piergiuseppe De Berardinis, Nancy L Haigwood
Published 2012-01-01

Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal Challenge.

by Iskra Tuero, Venkatramanan Mohanram, Thomas Musich, Leia Miller, Diego A Vargas-Inchaustegui, Thorsten Demberg, David Venzon, Irene Kalisz, V S Kalyanaraman, Ranajit Pal, Maria Grazia Ferrari, Celia LaBranche, David C Montefiori, Mangala Rao, Monica Vaccari, Genoveffa Franchini, Susan W Barnett, Marjorie Robert-Guroff
Published 2015-08-01

Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C.

by Jeff Alexander, Jason Mendy, Lo Vang, Jenny B Avanzini, Fermin Garduno, Darly J Manayani, Glenn Ishioka, Peggy Farness, Li-Hua Ping, Ronald Swanstrom, Robert Parks, Hua-Xin Liao, Barton F Haynes, David C Montefiori, Celia LaBranche, Jonathan Smith, Marc Gurwith, Tim Mayall
Published 2013-01-01