A strategy to incorporate prior knowledge into correlation network cutoff selection

by Elisa Benedetti, Maja Pučić-Baković, Toma Keser, Nathalie Gerstner, Mustafa Büyüközkan, Tamara Štambuk, Maurice H. J. Selman, Igor Rudan, Ozren Polašek, Caroline Hayward, Hassen Al-Amin, Karsten Suhre, Gabi Kastenmüller, Gordan Lauc, Jan Krumsiek
Published 2020-10-01

A Workflow for Missing Values Imputation of Untargeted Metabolomics Data

by Tariq Faquih, Maarten van Smeden, Jiao Luo, Saskia le Cessie, Gabi Kastenmüller, Jan Krumsiek, Raymond Noordam, Diana van Heemst, Frits R. Rosendaal, Astrid van Hylckama Vlieg, Ko Willems van Dijk, Dennis O. Mook-Kanamori
Published 2020-11-01

Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism

by Valentina S. Klaus, Sonja C. Schriever, José Manuel Monroy Kuhn, Andreas Peter, Martin Irmler, Janina Tokarz, Cornelia Prehn, Gabi Kastenmüller, Johannes Beckers, Jerzy Adamski, Alfred Königsrainer, Timo D. Müller, Martin Heni, Matthias H. Tschöp, Paul T. Pfluger, Dominik Lutter
Published 2021-11-01

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study.

by Elisabeth Altmaier, Cristina Menni, Margit Heier, Christa Meisinger, Barbara Thorand, Jan Quell, Michael Kobl, Werner Römisch-Margl, Ana M Valdes, Massimo Mangino, Melanie Waldenberger, Konstantin Strauch, Thomas Illig, Jerzy Adamski, Tim Spector, Christian Gieger, Karsten Suhre, Gabi Kastenmüller
Published 2016-01-01

Body fat free mass is associated with the serum metabolite profile in a population-based study.

by Carolin Jourdan, Ann-Kristin Petersen, Christian Gieger, Angela Döring, Thomas Illig, Rui Wang-Sattler, Christa Meisinger, Annette Peters, Jerzy Adamski, Cornelia Prehn, Karsten Suhre, Elisabeth Altmaier, Gabi Kastenmüller, Werner Römisch-Margl, Fabian J Theis, Jan Krumsiek, H-Erich Wichmann, Jakob Linseisen
Published 2012-01-01

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality.

by Johannes Raffler, Nele Friedrich, Matthias Arnold, Tim Kacprowski, Rico Rueedi, Elisabeth Altmaier, Sven Bergmann, Kathrin Budde, Christian Gieger, Georg Homuth, Maik Pietzner, Werner Römisch-Margl, Konstantin Strauch, Henry Völzke, Melanie Waldenberger, Henri Wallaschofski, Matthias Nauck, Uwe Völker, Gabi Kastenmüller, Karsten Suhre
Published 2015-09-01

Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.

by Cornelia Then, Simone Wahl, Anna Kirchhofer, Harald Grallert, Susanne Krug, Gabi Kastenmüller, Werner Römisch-Margl, Melina Claussnitzer, Thomas Illig, Margit Heier, Christa Meisinger, Jerzy Adamski, Barbara Thorand, Cornelia Huth, Annette Peters, Cornelia Prehn, Ina Heukamp, Helmut Laumen, Andreas Lechner, Hans Hauner, Jochen Seissler
Published 2013-01-01

Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population

by Bing Yu, Claudia Flexeder, Robert W. McGarrah, Annah Wyss, Alanna C. Morrison, Kari E. North, Eric Boerwinkle, Gabi Kastenmüller, Christian Gieger, Karsten Suhre, Stefan Karrasch, Annette Peters, Gregory R. Wagner, Gregory A. Michelotti, Robert P. Mohney, Holger Schulz, Stephanie J. London
Published 2019-04-01

Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection

by Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P. W. Auyeung, Jian’an Luan, Chris Finan, Juan P. Casas, Rachel Ostroff, Steve A. Williams, Gabi Kastenmüller, Markus Ralser, Eric R. Gamazon, Nicholas J. Wareham, Aroon D. Hingorani, Claudia Langenberg
Published 2021-02-01

Genetic architecture of host proteins involved in SARS-CoV-2 infection

by Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P. W. Auyeung, Jian’an Luan, Chris Finan, Juan P. Casas, Rachel Ostroff, Steve A. Williams, Gabi Kastenmüller, Markus Ralser, Eric R. Gamazon, Nicholas J. Wareham, Aroon D. Hingorani, Claudia Langenberg
Published 2020-12-01

Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse

by Jialing Huang, Marcela Covic, Cornelia Huth, Martina Rommel, Jonathan Adam, Sven Zukunft, Cornelia Prehn, Li Wang, Jana Nano, Markus F. Scheerer, Susanne Neschen, Gabi Kastenmüller, Christian Gieger, Michael Laxy, Freimut Schliess, Jerzy Adamski, Karsten Suhre, Martin Hrabe de Angelis, Annette Peters, Rui Wang-Sattler
Published 2021-02-01

Differences between human plasma and serum metabolite profiles.

by Zhonghao Yu, Gabi Kastenmüller, Ying He, Petra Belcredi, Gabriele Möller, Cornelia Prehn, Joaquim Mendes, Simone Wahl, Werner Roemisch-Margl, Uta Ceglarek, Alexey Polonikov, Norbert Dahmen, Holger Prokisch, Lu Xie, Yixue Li, H-Erich Wichmann, Annette Peters, Florian Kronenberg, Karsten Suhre, Jerzy Adamski, Thomas Illig, Rui Wang-Sattler
Published 2011-01-01

Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction

by Cavin K. Ward-Caviness, Golareh Agha, Brian H. Chen, Liliane Pfeiffer, Rory Wilson, Petra Wolf, Christian Gieger, Joel Schwartz, Pantel S. Vokonas, Lifang Hou, Allan C. Just, Stefania Bandinelli, Dena G. Hernandez, Andrew B. Singleton, Holger Prokisch, Thomas Meitinger, Gabi Kastenmüller, Luigi Ferrucci, Andrea A. Baccarelli, Melanie Waldenberger, Annette Peters
Published 2018-12-01

Connecting genetic risk to disease end points through the human blood plasma proteome

by Karsten Suhre, Matthias Arnold, Aditya Mukund Bhagwat, Richard J. Cotton, Rudolf Engelke, Johannes Raffler, Hina Sarwath, Gaurav Thareja, Annika Wahl, Robert Kirk DeLisle, Larry Gold, Marija Pezer, Gordan Lauc, Mohammed A. El-Din Selim, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Yasmin A. Mohamoud, Joel Malek, Konstantin Strauch, Harald Grallert, Annette Peters, Gabi Kastenmüller, Christian Gieger, Johannes Graumann
Published 2017-02-01

Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome

by Karsten Suhre, Matthias Arnold, Aditya Mukund Bhagwat, Richard J. Cotton, Rudolf Engelke, Johannes Raffler, Hina Sarwath, Gaurav Thareja, Annika Wahl, Robert Kirk DeLisle, Larry Gold, Marija Pezer, Gordan Lauc, Mohammed A. El-Din Selim, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Yasmin A. Mohamoud, Joel Malek, Konstantin Strauch, Harald Grallert, Annette Peters, Gabi Kastenmüller, Christian Gieger, Johannes Graumann
Published 2017-04-01

Genetic diagnosis of Mendelian disorders via RNA sequencing

by Laura S. Kremer, Daniel M. Bader, Christian Mertes, Robert Kopajtich, Garwin Pichler, Arcangela Iuso, Tobias B. Haack, Elisabeth Graf, Thomas Schwarzmayr, Caterina Terrile, Eliška Koňaříková, Birgit Repp, Gabi Kastenmüller, Jerzy Adamski, Peter Lichtner, Christoph Leonhardt, Benoit Funalot, Alice Donati, Valeria Tiranti, Anne Lombes, Claude Jardel, Dieter Gläser, Robert W. Taylor, Daniele Ghezzi, Johannes A. Mayr, Agnes Rötig, Peter Freisinger, Felix Distelmaier, Tim M. Strom, Thomas Meitinger, Julien Gagneur, Holger Prokisch
Published 2017-06-01

Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome

by Matthias Arnold, Kwangsik Nho, Alexandra Kueider-Paisley, Tyler Massaro, Kevin Huynh, Barbara Brauner, Siamak MahmoudianDehkordi, Gregory Louie, M. Arthur Moseley, J. Will Thompson, Lisa St John-Williams, Jessica D. Tenenbaum, Colette Blach, Rui Chang, Roberta D. Brinton, Rebecca Baillie, Xianlin Han, John Q. Trojanowski, Leslie M. Shaw, Ralph Martins, Michael W. Weiner, Eugenia Trushina, Jon B. Toledo, Peter J. Meikle, David A. Bennett, Jan Krumsiek, P. Murali Doraiswamy, Andrew J. Saykin, Rima Kaddurah-Daouk, Gabi Kastenmüller
Published 2020-03-01

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

by Joris Deelen, Johannes Kettunen, Krista Fischer, Ashley van der Spek, Stella Trompet, Gabi Kastenmüller, Andy Boyd, Jonas Zierer, Erik B. van den Akker, Mika Ala-Korpela, Najaf Amin, Ayse Demirkan, Mohsen Ghanbari, Diana van Heemst, M. Arfan Ikram, Jan Bert van Klinken, Simon P. Mooijaart, Annette Peters, Veikko Salomaa, Naveed Sattar, Tim D. Spector, Henning Tiemeier, Aswin Verhoeven, Melanie Waldenberger, Peter Würtz, George Davey Smith, Andres Metspalu, Markus Perola, Cristina Menni, Johanna M. Geleijnse, Fotios Drenos, Marian Beekman, J. Wouter Jukema, Cornelia M. van Duijn, P. Eline Slagboom
Published 2019-08-01