The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury.

by Jaklien C Leemans, Loes M Butter, Wilco P C Pulskens, Gwendoline J D Teske, Nike Claessen, Tom van der Poll, Sandrine Florquin
Published 2009-01-01

Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos.

by Daniel H Paris, Femke Stephan, Ingrid Bulder, Diana Wouters, Tom van der Poll, Paul N Newton, Nicholas P J Day, Sacha Zeerleder
Published 2015-01-01

A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).

by Liesbeth M Kager, W Joost Wiersinga, Joris J T H Roelofs, Onno J de Boer, Hartmut Weiler, Cornelis van 't Veer, Tom van der Poll
Published 2014-04-01

Toll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo.

by Sacha F de Stoppelaar, Theodora A M Claushuis, Marianne C L Schaap, Baidong Hou, Tom van der Poll, Rienk Nieuwland, Cornelis van 't Veer
Published 2016-01-01

Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis.

by Miriam H P van Lieshout, Adam A Anas, Sandrine Florquin, Baidong Hou, Cornelis van't Veer, Alex F de Vos, Tom van der Poll
Published 2014-09-01

Dynamics of peripheral blood lymphocyte subpopulations in the acute and subacute phase of Legionnaires' disease.

by Cornelis P C de Jager, Eugenie F A Gemen, Jacqueline Leuvenink, Mirrian Hilbink, Robert J F Laheij, Tom van der Poll, Peter C Wever
Published 2013-01-01

Intestinal colonization with Enterococcus faecium does not influence pulmonary defense against Pseudomonas aeruginosa in mice.

by Masja Leendertse, Rob J L Willems, Ida A J Giebelen, Joris J T H Roelofs, Janetta Top, Marc J M Bonten, Tom van der Poll
Published 2009-08-01

Streptococcus pneumoniae serine protease HtrA, but not SFP or PrtA, is a major virulence factor in pneumonia.

by Sacha F de Stoppelaar, Hester J Bootsma, Aldert Zomer, Joris J T H Roelofs, Peter W M Hermans, Cornelis van 't Veer, Tom van der Poll
Published 2013-01-01

TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion.

by Pieter J Bakker, Angelique M Scantlebery, Loes M Butter, Nike Claessen, Gwendoline J D Teske, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Published 2015-01-01

Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis

by M. Isabel García-Laorden, Ingrid Stroo, Sanne Terpstra, Sandrine Florquin, Jan Paul Medema, Cornelis van´t Veer, Alex F. de Vos, Tom van der Poll
Published 2017-01-01

Pulmonary Procoagulant and Innate Immune Responses in Critically Ill COVID-19 Patients

by Esther J. Nossent, Esther J. Nossent, Alex R. Schuurman, Alex R. Schuurman, Tom D.Y. Reijnders, Tom D.Y. Reijnders, Anno Saris, Anno Saris, Ilse Jongerius, Ilse Jongerius, Siebe G. Blok, Heder de Vries, Heder de Vries, JanWillem Duitman, JanWillem Duitman, Anton Vonk Noordegraaf, Anton Vonk Noordegraaf, Lilian J. Meijboom, Lilian J. Meijboom, René Lutter, René Lutter, René Lutter, Leo Heunks, Leo Heunks, Harm Jan Bogaard, Harm Jan Bogaard, Tom van der Poll, Tom van der Poll, Tom van der Poll
Published 2021-05-01

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.

by Wanhai Qin, Xanthe Brands, Cornelis Van't Veer, Alex F de Vos, Jean-Claude Sirard, Joris J T H Roelofs, Brendon P Scicluna, Tom van der Poll
Published 2021-04-01

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

by Desiree Perlee, Alex F. deVos, Brendon P. Scicluna, Pablo Mancheño, Olga de laRosa, Wilfried Dalemans, Peter Nürnberg, Eleuterio Lombardo, Tom van derPoll
Published 2019-08-01

Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia.

by Florry E van den Boogaard, Jorrit J Hofstra, Cornelis van 't Veer, Marcel M Levi, Joris J T H Roelofs, Tom van der Poll, Marcus J Schultz
Published 2015-01-01

Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia.

by Dana C Blok, Koenraad F van der Sluijs, Sandrine Florquin, Onno J de Boer, Cornelis van 't Veer, Alex F de Vos, Tom van der Poll
Published 2013-01-01

Toll-Like Receptor 9 Enhances Bacterial Clearance and Limits Lung Consolidation in Murine Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus

by Anne Jan van der Meer, Achmed Achouiti, Arie van der Ende, Aicha Ait Soussan, Sandrine Florquin, Alex de Vos, Sacha S Zeerleder, Tom van der Poll
Published 2016-06-01

Long-term safety and effectiveness of canakinumab therapy in patients with cryopyrin-associated periodic syndrome: results from the β-Confident Registry

by Ulrich A Walker, Jasmin B Kuemmerle-Deschner, Jeremy Levy, Eleni Vritzali, Hal M Hoffman, Tom van der Poll, PHILIP N HAWKINS, Hugh H Tilson, Stephanie Noviello
Published 2021-08-01

Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model

by Jack Yang, Ivan Ramirez Moral, Cornelis van ’t Veer, Alex F. de Vos, Regina de Beer, Joris J. T. H. Roelofs, B. Paul Morgan, Tom van der Poll
Published 2019-07-01

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

by Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos
Published 2019-01-01

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

by Tijmen J Hommes, Miriam H van Lieshout, Cornelis van 't Veer, Sandrine Florquin, Hester J Bootsma, Peter W Hermans, Alex F de Vos, Tom van der Poll
Published 2015-01-01