Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC

by Shipra Das, Olga Anczuków, Martin Akerman, Adrian R. Krainer
Published 2012-02-01

Deletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing.

by Stephanie D Shaw, Sutapa Chakrabarti, Gourisankar Ghosh, Adrian R Krainer
Published 2007-09-01

Delivery of GalNAc-Conjugated Splice-Switching ASOs to Non-hepatic Cells through Ectopic Expression of Asialoglycoprotein Receptor

by Juergen Scharner, Sabrina Qi, Frank Rigo, C. Frank Bennett, Adrian R. Krainer
Published 2019-06-01

Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides

by Zhenxun Wang, Hyun Yong Jeon, Frank Rigo, C. Frank Bennett, Adrian R. Krainer
Published 2012-01-01

Enhancement of SMN2 exon 7 inclusion by antisense oligonucleotides targeting the exon.

by Yimin Hua, Timothy A Vickers, Brenda F Baker, C Frank Bennett, Adrian R Krainer
Published 2007-04-01

Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65).

by Michelle L Hastings, Eric Allemand, Dominik M Duelli, Michael P Myers, Adrian R Krainer
Published 2007-06-01

A Broad Set of Chromatin Factors Influences Splicing.

by Eric Allemand, Michael P Myers, Jose Garcia-Bernardo, Annick Harel-Bellan, Adrian R Krainer, Christian Muchardt
Published 2016-09-01

Identification of synaptic targets of Drosophila pumilio.

by Gengxin Chen, Wanhe Li, Qing-Shuo Zhang, Michael Regulski, Nishi Sinha, Jody Barditch, Tim Tully, Adrian R Krainer, Michael Q Zhang, Josh Dubnau
Published 2008-02-01

Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia

by Masahiko Ajiro, Tomonari Awaya, Young Jin Kim, Kei Iida, Masatsugu Denawa, Nobuo Tanaka, Ryo Kurosawa, Shingo Matsushima, Saiko Shibata, Tetsunori Sakamoto, Rolenz Studer, Adrian R. Krainer, Masatoshi Hagiwara
Published 2021-07-01

HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism

by Sebastien M. Weyn-Vanhentenryck, Aldo Mele, Qinghong Yan, Shuying Sun, Natalie Farny, Zuo Zhang, Chenghai Xue, Margaret Herre, Pamela A. Silver, Michael Q. Zhang, Adrian R. Krainer, Robert B. Darnell, Chaolin Zhang
Published 2014-03-01

Differential Functions of Splicing Factors in Mammary Transformation and Breast Cancer Metastasis

by SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura Urbanski, Adam Geier, Anil K. Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K. Muthuswamy, Adrian R. Krainer, Olga Anczuków
Published 2019-11-01

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

by Manaswini Sivaramakrishnan, Kathleen D. McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N. Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R. Krainer, Frédéric H.-T. Allain, Friedrich Metzger
Published 2017-11-01

Evidence generation and reproducibility in cell and gene therapy research: A call to action

by Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis
Published 2021-09-01