Experimental Parkinsonism Modulates Multiple Genes Involved in the Transduction of Dopaminergic Signals in the Striatum

by Maddalena Napolitano, Diego Centonze, Angelica Calce, Barbara Picconi, Stefania Spiezia, Alberto Gulino, Giorgio Bernardi, Paolo Calabresi
Published 2002-08-01

Inhibition of mitochondrial complex II alters striatal expression of genes involved in glutamatergic and dopaminergic signaling: possible implications for Huntington's disease

by Maddalena Napolitano, Diego Centonze, Paolo Gubellini, Silvia Rossi, Stefania Spiezia, Giorgio Bernardi, Alberto Gulino, Paolo Calabresi
Published 2004-03-01

Galectin-3 impairment of MYCN-dependent apoptosis-sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells.

by Veronica Veschi, Marialaura Petroni, Beatrice Cardinali, Carlo Dominici, Isabella Screpanti, Luigi Frati, Armando Bartolazzi, Alberto Gulino, Giuseppe Giannini
Published 2012-01-01

The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within...

by Pierdomenico Ruggeri, Antonietta R Farina, Natalia Di Ianni, Lucia Cappabianca, Marzia Ragone, Giulia Ianni, Alberto Gulino, Andrew R Mackay
Published 2014-01-01

TrkAIII Promotes Microtubule Nucleation and Assembly at the Centrosome in SH-SY5Y Neuroblastoma Cells, Contributing to an Undifferentiated Anaplastic Phenotype

by Antonietta R. Farina, Natalia Di Ianni, Lucia Cappabianca, Pierdomenico Ruggeri, Marzia Ragone, Giulia Ianni, Alberto Gulino, Andrew R. Mackay
Published 2013-01-01

KCTD11 Tumor Suppressor Gene Expression Is Reduced in Prostate Adenocarcinoma

by Francesca Zazzeroni, Daniela Nicosia, Alessandra Tessitore, Rita Gallo, Daniela Verzella, Mariafausta Fischietti, Davide Vecchiotti, Luca Ventura, Daria Capece, Alberto Gulino, Edoardo Alesse
Published 2014-01-01

Human Papilloma Virus-Dependent HMGA1 Expression Is a Relevant Step in Cervical Carcinogenesis

by Massimiliano Mellone, Christian Rinaldi, Isabella Massimi, Marialaura Petroni, Veronica Veschi, Claudio Talora, Silvia Truffa, Helena Stabile, Luigi Frati, Isabella Screpanti, Alberto Gulino, Giuseppe Giannini
Published 2008-08-01

A novel, non-canonical splice variant of the Ikaros gene is aberrantly expressed in B-cell lymphoproliferative disorders.

by Daria Capece, Francesca Zazzeroni, Maria Michela Mancarelli, Daniela Verzella, Mariafausta Fischietti, Ambra Di Tommaso, Rita Maccarone, Sara Plebani, Mauro Di Ianni, Alberto Gulino, Edoardo Alesse
Published 2013-01-01

Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy.

by Sonia Coni, Laura Antonucci, Davide D'Amico, Laura Di Magno, Paola Infante, Enrico De Smaele, Giuseppe Giannini, Lucia Di Marcotullio, Isabella Screpanti, Alberto Gulino, Gianluca Canettieri
Published 2013-01-01

An Integrated Approach Identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated Genes in Developing Cerebellum and Medulloblastoma

by Enrico De Smaele, Caterina Fragomeli, Elisabetta Ferretti, Marianna Pelloni, Agnese Po, Gianluca Canettieri, Sonia Coni, Lucia Di Marcotullio, Azzura Greco, Marta Moretti, Concezio Di Rocco, Simona Pazzaglia, Marella Maroder, Isabella Screpanti, Giuseppe Giannini, Alberto Gulino
Published 2008-01-01

Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL

by Maria Pelullo, Roberta Quaranta, Claudio Talora, Saula Checquolo, Samantha Cialfi, Maria Pia Felli, Geertruy te Kronnie, Chiara Borga, Zein Mersini Besharat, Rocco Palermo, Lucia Di Marcotullio, Anthony J. Capobianco, Alberto Gulino, Isabella Screpanti, Diana Bellavia
Published 2014-12-01

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

by Enrico De Smaele, Lucia Di Marcotullio, Marta Moretti, Marianna Pelloni, Maria Anna Occhione, Paola Infante, Danilo Cucchi, Azzura Greco, Laura Pietrosanti, Jelena Todorovic, Sonia Coni, Gianluca Canettieri, Elisabetta Ferretti, Roberto Bei, Marella Maroder, Isabella Screpanti, Alberto Gulino
Published 2011-04-01

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

by Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Romina Alfonsi, Daniela Mazzà, Mariangela Siler, Sonia Coni, Agnese Po, Marialaura Petroni, Elisabetta Ferretti, Mattia Mori, Enrico De Smaele, Gianluca Canettieri, Carlo Capalbo, Marella Maroder, Isabella Screpanti, Marcel Kool, Stefan M. Pfister, Daniele Guardavaccaro, Alberto Gulino, Lucia Di Marcotullio
Published 2018-03-01

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

by Francesca Bufalieri, Paola Infante, Flavia Bernardi, Miriam Caimano, Paolo Romania, Marta Moretti, Ludovica Lospinoso Severini, Julie Talbot, Ombretta Melaiu, Mirella Tanori, Laura Di Magno, Diana Bellavia, Carlo Capalbo, Stéphanie Puget, Enrico De Smaele, Gianluca Canettieri, Daniele Guardavaccaro, Luca Busino, Angelo Peschiaroli, Simonetta Pazzaglia, Giuseppe Giannini, Gerry Melino, Franco Locatelli, Alberto Gulino, Olivier Ayrault, Doriana Fruci, Lucia Di Marcotullio
Published 2019-07-01